Tag: M.W=100-200

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a document, author is Chitara, Manoj K., introduce the new discover, Product Details of 89-01-0.

Impact of the alkaloid colletotrichumine A on the pathogenicity of Colletotrichum capsici in Capsicum annum L

Herein we report a study examining the effects of colletotrichumine A, an indole-pyrazine alkaloid isolated from the anthracnose pathogen Colletotrichum capsici, on chilli plants. A colletotrichumine A-pathogen combination was more toxic to the host than individual inoculations of colletotrichumine A or the pathogen. The colletotrichumine A-pathogen combination led to an increased activity of defense related enzymes viz. PPO and SOD, while levels of the lignification enzymes PAL and PO decreased. Higher levels of phenols including catechin and ferulic acid were also observed with the colletotrichumine A-pathogen combination compared to individual treatment. The likely role of colletotrichumine A during chilli anthracnose infection is supported by histochemical analysis of infected plants that showed increased cell death after infection.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 89-01-0 is helpful to your research. Product Details of 89-01-0.

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 33332-25-1, Name is Methyl 5-chloropyrazine-2-carboxylate, SMILES is ClC1=CN=C(C=N1)C(=O)OC, in an article , author is Healy, Colm, once mentioned of 33332-25-1, Formula: C6H5ClN2O2.

Thermal decomposition of hybrid ultramicroporous materials (HUMs)

Hybrid Ultramicroporous Materials (HUMs) are porous coordination materials with exemplary gas sorption and separation characteristics, but relatively poor thermal stability when compared to other porous coordination polymers or metal-organic frameworks (MOFs). The origin of this poor thermal stability has not yet been experimentally verified. Therefore, we investigate the thermal decomposition mechanisms of representative HUMs with the general formulae [M(SiF6)(L)(2)] or [M(SiF6)(L)(H2O)(2)], where M = Ni(ii), Cu(ii) or Zn(ii) and L = pyrazine or 4,4 ‘-bipyridine. We find that two decomposition mechanisms dominate: (i) the fragmentation of the XF62- pillar into gaseous XF4 and fluoride, and (ii) direct sublimation of the N-donor ligand. The former process dictates the overall thermal stability of the material. We also demonstrate that HF is a possible decomposition product from certain hydrated HUM materials.

Interested yet? Read on for other articles about 33332-25-1, you can contact me at any time and look forward to more communication. Formula: C6H5ClN2O2.

Related Products of 33332-25-1, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 33332-25-1, Name is Methyl 5-chloropyrazine-2-carboxylate, SMILES is ClC1=CN=C(C=N1)C(=O)OC, belongs to Pyrazines compound. In a article, author is Wang, Shijun, introduce new discover of the category.

Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents

Background: Increasingly, different heterocyclic systems have been introduced into the steroid nucleus to significantly enhance the antitumor activities of steroid molecules. However, in this study, few literature precedents describing the pyrazine heterocyclic-condensed modification to an A-ring of steroid monomers were found, although the pyrazine group is thought to be essential for the potent anticancer activity of clinically relevant drugs and natural steroid dimers. Methods and Results: Two series of novel A-ring fused steroidal pyrazines were designed and efficiently synthesized from commercially available progesterone via key alpha-ketoenol intermediates. Through a cell counting kit-8 cytotoxic assay of 36 derivatives for three tumor cells, 14 compounds displayed significant antiproliferative activity compared to 5-fluorouracil, especially for human prostatic tumor cells (PC-3) in vitro. Further mechanistic studies indicated that the most active compound, 12n (IC50, 0.93 mu M; SI, 28.71), could induce the cell apoptosis of PC-3 cells in a dose-dependent manner and cause cell cycle arrest in the G2/M phase. The molecular docking study suggested that compound 12n fitted the active sites of cytochrome P450 17A1 (6CIZ) well. Conclusions: 12n might serve as a promising lead compound for the development of novel anticancer drugs. This facile ring-closing strategy may provide a novel and promising avenue for the cycloaddition reaction of the steroidal skeleton through alpha-ketoenol intermediates.

Related Products of 33332-25-1, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 33332-25-1.

33332-25-1, Name is Methyl 5-chloropyrazine-2-carboxylate, molecular formula is C6H5ClN2O2, belongs to Pyrazines compound, is a common compound. In a patnet, author is Chen, Yuan, once mentioned the new application about 33332-25-1, Formula: C6H5ClN2O2.

Two Zn(II)-based coordination polymers: treatment effect on the cardiac arrest induced by anesthesia by regulating Sirt1 expression

By applying a mixed-ligand approach, two new Zn(II)-containing coordination polymers (CPs) with the chemical formula of {Zn(TDC)(TPP)(0.5)center dot H2O}(n) (1) and {[Zn-2(2,6-NDC)(2)(TPP)]center dot MeCN center dot 3H(2)O}(n) (2) (TPP = 2,3,5,6-tetra(pyridin-4-yl)pyrazine, H2TDC = 2,5-thiophenedicarboxylic acid, 2,6-H2NDC = 2,6-naphthalic acid), have been synthesized by a semi-rigid tetrapyridine ligand and auxiliary dicarboxylic ligands. In biological functional study, compounds 1 and 2 was investigated for the treatment of cardiac arrest induced by anesthesia. The cardiac arrest-cardiopulmonary resuscitation model was established, followed by the compounds given for treatment. The enzyme linked immunosorbent assay (ELISA) detection kit was used in this experiment for measuring the content of cardiac troponin T and B brain natriuretic peptide after compounds treatment. Next, the relative expression level of the Sirt1 in the rat myocardial tissue was measured with real time reverse transcription-polymerase chain reaction (RT-PCR).

If you¡¯re interested in learning more about 33332-25-1. The above is the message from the blog manager. Formula: C6H5ClN2O2.

Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 20737-42-2, Name is 3-Oxo-3,4-dihydropyrazine-2-carboxylic acid. In a document, author is Evenson, Sean J., introducing its new discovery. Safety of 3-Oxo-3,4-dihydropyrazine-2-carboxylic acid.

Minimizing Polymer Band Gap via Donor-Acceptor Frameworks: Poly(dithieno[3,2-b:2 ‘,3 ‘-d]pyrrole-alt-thieno[3,4-b]pyrazine)s as Illustrative Examples of Challenges and Misconceptions

Donor-acceptor (D-A) frameworks have been produced via the copolymerization of the strong donor dithieno[3,2-b:2 ‘,3 ‘-d]pyrrole (DTP) with ambipolar thieno[3,4-b]pyrazine (TP) units to generate soluble, processible materials with band gaps as low as 0.8 eV. Optical and electronic characterization of the DTP-TP copolymers illustrate common misconceptions in the relative contributions of the comonomers to the D-A framework, as well as highlighting the challenges of minimizing band gap while also retaining desirable frontier orbital energies for application to technological devices.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 20737-42-2 help many people in the next few years. Safety of 3-Oxo-3,4-dihydropyrazine-2-carboxylic acid.

Reference of 89-01-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a article, author is Tan, Yee Seng, introduce new discover of the category.

Crystal structure of catena-poly[(mu(2)-pyrazine-N,N ‘)-bis(O,O ‘-diisopropyldithiophosphato-S,S ‘)cadmium(II) acetonitrile di-solvate], [C16H32CdN2O4P2S4 center dot 2(C2H3N)](n)

C20H38CdN4O4P2S4, triclinic, P (1) over bar (no. 2), a = 9.6352(2) angstrom, b = 11.3986(2) angstrom, c = 14.8017(3) angstrom, alpha = 85.713(2)degrees, beta = 89.877(2)degrees, gamma = 86.048(2)degrees, V = 1617.23(6) angstrom(3), Z = 2, R-gt(F) = 0.0285, wR(ref)(F-2) = 0.0829, T = 100 K.

Reference of 89-01-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 89-01-0.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 123-32-0, Name is 2,5-Dimethylpyrazine, formurla is C6H8N2. In a document, author is Bagheri, Sotoodeh, introducing its new discovery. HPLC of Formula: C6H8N2.

The influence of CH … pi interaction on coupling constants across N … H-F hydrogen bond in a substituted T-shaped configuration: a theoretical study

For studying the influence of CH horizontal ellipsis pi interaction on coupling constants across N horizontal ellipsis H-F hydrogen bond in a substituted T-shaped configuration, X-benzene perpendicular to(FH horizontal ellipsis pyrazine horizontal ellipsis HF) complexes are chosen as a working model. NMR calculations are performed at B3LYP/6-311++G(d,p) and PBE0/6-311++G(d,p) levels. Here, correlations between energetic, geometrical and topological parameters and coupling constants are investigated. The results indicate that direct correlations exist between strength of N horizontal ellipsis H hydrogen bond, electron-donating power of substituents and |(2h)J(N-F)|. Also, |(2h)J(N-F)| increases as cooperative and synergistic energies become more negative. These behaviours are reversed for (1h)J(N-H). Due to contradictory behaviours of FC and PSO terms, an irregular trend is observed for (1)J(H-F).

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 123-32-0 help many people in the next few years. HPLC of Formula: C6H8N2.

22047-25-2, Name is Acetylpyrazine, molecular formula is C6H6N2O, belongs to Pyrazines compound, is a common compound. In a patnet, author is Arar, Sharif, once mentioned the new application about 22047-25-2, Name: Acetylpyrazine.

New forced degradation products of vildagliptin: Identification and structural elucidation using LC-MS, with proposed formation mechanisms

A new and simple RP-HPLC-UV method was developed for well-separation of vildagliptin raw material and its degradation products at different conditions; it uses of ammonium acetate buffer at pH= 7.5 and methanol with Athena C18 -WP (250 mm) column. Results show that six degradants have been identified using LC-MS technique, in addition to the NMR approach in some cases. One degradant at relative retention time (RRT) 1.3 was formed under acidic condition and designated as 2-((1R, 3S, 5R, 7S)-3-hydroxyadamantan-1-yl) hexahydropyrrolo[1,2-a]pyrazine-1,4-dione at m/z = 304. Three degradants were formed under various conditions of basic hydrolysis at RRTs 1.2, 0.6 and 0.4 with following names and molar masses (m/z), respectively: 1-(((1S, 3S, 5S, 7S)-1,3-dihydroxyadamantan-2-yl)glycyl)pyrrolidine-2-carboxamide at m/z = 337.2, 1-(((1R, 3S, 5R, 7S)-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carboxamide at m/z = 321.1 and (1,4-dioxo-1,4,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-3-yl)glycylproline at m/z = 322.6. Another three degradants were also formed under oxidative oxidations of vildagliptin, one at RRT 0.38 and designated as N-hydroxy-N-((1R, 3S, 5R, 7S)-3-hydroxyadamantan-1-yl) glycinate with m/z 241.1, the second one was identical to that formed under basic hydrolysis at RRT 0.6 and the last one has RRT 0.8 and was identified as (1S, 3R, 5R, 7S)-3-(hydroxyamino)adamantan-1-ol at m/z 183.1. Formation mechanisms for the degradation products were described.

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Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products, HPLC of Formula: C5H3N3, 19847-12-2, Name is Pyrazinecarbonitrile, molecular formula is C5H3N3, belongs to Pyrazines compound. In a document, author is Mangrolia, Upasana, introduce the new discover.

Staphylococcus xylosus VITURAJ10: Pyrrolo [1,2 alpha] pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl) (PPDHMP) producing, potential probiotic strain with antibacterial and anticancer activity

In the present study bacterial strain (VITURAJ10), isolated from goat milk was characterised for its probiotic potential. The various probiotic traits included tolerance to acidic pH (up to pH 3), bile salts (0.3%) and transit gut environment (simulated with digestive juices such as pepsin, Oxgall and pancreatin). The isolate could withstand high NaCl concentrations in the growth medium, showed inability to produce hemolysin and did not hydrolyse mucin. VITURAJ10 was capable of forming biofilm and produced exopolysachharide. The bioactive metabolites produced by the isolate were extracted and they showed growth suppressing activity towards pathogenic strains such as Escherichia coli, Salmonella enterica and Staphylococcus aureus. The crude extract was fractionated with solid phase extraction (SPE) chromatography and the fractions 10 and 12 were found to be effective against the bacterial pathogens. The fractions were further gauged for cytotoxic activity against MCF-7 cell line by MIT assay. The biologically significant compounds identified through GC-MS and FT-IR analysis in the fractions were, Actinomycin D, Pyrrolo [1,2 alpha] Pyrazine-1,4-Dione, Hexahydro 3 (2 Methylpropyl)(PPDHMP) and Didemnin B. The phylogenetic taxonomy of the isolate revealed the isolate to be the closest neighbour of Staphylococcus xylosus VITURAJ10 (GenBank accession no.KX770743.1 ) as per the16S rRNA gene sequencing and subsequent phylogenetic tree analysis.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 19847-12-2. HPLC of Formula: C5H3N3.

Electric Literature of 19847-12-2, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 19847-12-2, Name is Pyrazinecarbonitrile, SMILES is N#CC1=NC=CN=C1, belongs to Pyrazines compound. In a article, author is Patil, Mahadev, introduce new discover of the category.

Synthesis, molecular docking studies, and in vitro antimicrobial evaluation of piperazine and triazolo-pyrazine derivatives

For this work, two series of new piperazine derivatives (3a-o) and triazolo-pyrazine derivatives (3p-t) were synthesized in a single-step reaction. All twenty adducts were obtained in good to high yields and fully characterized by H-1 NMR, C-13 NMR, IR, and mass spectrometry techniques. To further confirm the chemical identity of the adducts, a crystal of N-{[(4-chlorophenyl)-3-(trifluoromethyl)]-5,6-dihydro-[1,2,4]triazolo[4,3-a]}pyrazine-7(8H)-carboxamide (3t) was prepared and analyzed using X-ray crystallography. In vitro screening of the antimicrobial activity of all compounds (3a-t) was evaluated against five bacterial and two fungal strains. This study disclosed that N-{[(3-chlorophenyl)]-4-(dibenzo[b,f][1,4]thiazepin-11-yl)}piperazine-1-carboxamide (3o) was the superior antimicrobial with good growth inhibition against A. baumannii. Furthermore, the results from the performed molecular docking studies were promising, since the observed data could be used to develop more potent antimicrobials.

Electric Literature of 19847-12-2, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 19847-12-2.