Synthesis and anti-oxidative activities of resveratrol analogs was written by Liu, Ming;Liu, Wei;Jiang, Jie;Cheng, Qian;Ren, Jun-lan. And the article was included in Zhongguo Xinyao Zazhi in 2011.Safety of (3,5,6-Trimethylpyrazin-2-yl)methanol This article mentions the following:
Objective: To synthesize the resveratrol analogs with more potent anti-oxidative activities. Methods: The A ring of resveratrol was substituted by TMP ring or 4-aminoquinoline ring. The DPPH radical scavenging abilities of the target mols. 9, 12 and intermediate 8, 11 were tested. Results and Conclusion: Two novel resveratrol analogs were synthesized, and their structures were confirmed by MS and 1H-NMR. Compound 8 possesses more potent DPPH radical scavenging ability than resveratrol at low concentration and holds potent anti-oxidative activity. In the experiment, the researchers used many compounds, for example, (3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3Safety of (3,5,6-Trimethylpyrazin-2-yl)methanol).
(3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3) belongs to pyrazine derivatives. Pyrazine has the elements of symmetry for the point group D2h. It has three mutually perpendicular two-fold axes. It also has three mutually perpendicular planes of symmetry. As a result, pyrazine also has a centre of symmetry. Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes.Safety of (3,5,6-Trimethylpyrazin-2-yl)methanol