Category: 89-01-0

Synthetic Route of 89-01-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to pyrazines compound. In a article, author is Tan, Yee Seng, introduce new discover of the category.

C20H38CdN4O4P2S4, triclinic, P (1) over bar (no. 2), a = 9.6352(2) angstrom, b = 11.3986(2) angstrom, c = 14.8017(3) angstrom, alpha = 85.713(2)degrees, beta = 89.877(2)degrees, gamma = 86.048(2)degrees, V = 1617.23(6) angstrom(3), Z = 2, R-gt(F) = 0.0285, wR(ref)(F-2) = 0.0829, T = 100 K.

Synthetic Route of 89-01-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 89-01-0.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Reference of 89-01-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a article, author is Tan, Yee Seng, introduce new discover of the category.

C20H38CdN4O4P2S4, triclinic, P (1) over bar (no. 2), a = 9.6352(2) angstrom, b = 11.3986(2) angstrom, c = 14.8017(3) angstrom, alpha = 85.713(2)degrees, beta = 89.877(2)degrees, gamma = 86.048(2)degrees, V = 1617.23(6) angstrom(3), Z = 2, R-gt(F) = 0.0285, wR(ref)(F-2) = 0.0829, T = 100 K.

Reference of 89-01-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 89-01-0.

Reference:
Pyrazine – Wikipedia,
,Pyrazine | C4H4N2 – PubChem

Application of 89-01-0, The chemical industry reduces the impact on the environment during synthesis 89-01-0, name is Pyrazine-2,3-dicarboxylic acid, I believe this compound will play a more active role in future production and life.

EXAMPLE 1 Preparation of 3-(5-chloropyrid -2-yl) carbamoyl-pyrazine 2 carboxylic acid In a clean, dry 500 ml R. B. flask charged acetic anhydride (162 gms) and pyrazine- 2,3, dicarboxylic acid (50 gms). The reaction mass was heated to 100-120 C. up to completion of reaction. After completion of reaction, the excess acetic anhydride was distilled under vacuum. Charged methylene dichloride (350 ml) to the above reaction mass followed by 2-amino-5- chloropyridine (40 gms) in a lot wise manner at room temperature in 30 min. The reaction mass was stirred at room temperature for 2 hrs; cooled the reaction mixture to 5-10 C. for 1 hr. The reaction mixture was filtered and washed with chilled methylene dichloride to obtain 3-(5-chloropyrid -2-yl) carbamoyl-pyrazine-2-carboxylic acid. Yield=82 gms. EXAMPLE 2; Preparation of 6-(5-chloropyrid-2-yl) 5,7-dioxo-5,6-dihydropyrrolo [3,4-b]-pyrazine; In a clean 500 ml R. B.flask charged pyrazine-2,3-dicaroxylic acid (50 gms) and acetic anhydride (162 gms). The reaction mass was heated to 110-120 C. till the completion of reaction to get pyrazine-2,3-dicarboxylic acid anhydride. After completion of the reaction, excess acetic anhydride distilled out under vacuum and furthermore charged methylene dichloride (315 ml) and 2-amino-5-chloropyridine (40 gms) in a lot wise manner at room temperature in 30 min. Further, reaction mixture was stirred for 2 hours at room temperature. The reaction mass was cooled to 5 to 10 C. for one hour, filtered the product and washed with chilled methylene dichloride. The solid was charged with methylene dichloride (235 ml), triethylamine (40.9 ml) at temp. 0-5 C. followed by ethyl chloroformate (28.1 ml). The reaction mass was stirred at 0-5 C. for 1 hr, added water (200 ml) to the reaction mixture and stirred the mass at room temperature for 1 hr to obtain the solids. The title compound thus separated was isolated by filtration.Yield=65 gms.The HPLC purity of this above product was above 99%.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Pyrazine-2,3-dicarboxylic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Sawant, Shrikant Dattatraya; Naik, Anil Mahadev; Kavishwar, Girish Arvind; Kavishwar, Smita Girish; US2008/146800; (2008); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Application of 89-01-0, The chemical industry reduces the impact on the environment during synthesis 89-01-0, name is Pyrazine-2,3-dicarboxylic acid, I believe this compound will play a more active role in future production and life.

Pyrazine-2,3-dicarboxylic acid (4.0 g, 23.8 mmol) was dissolved in acetic anhydride (30 mL).The reaction mixture was refluxed for one hour, and subsequently cooled down to 0 C in ice bath.The obtained crystals of pyrazine-2,3-dicarboxylic anhydride were filtered off (yield 70%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Pyrazine-2,3-dicarboxylic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Semelkova, Lucia; Jano?cova, Petra; Fernandes, Carlos; Bouz, Ghada; Jand?Ourek, Ond?ej; Kone?na, Klara; Paterova, Pavla; Navratilova, Lucie; Kune?, Ji?i; Dole?al, Martin; Zitko, Jan; Molecules; vol. 22; 9; (2017);,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

In an article, author is Regenauer, Nicolas, I, once mentioned the application of 89-01-0, Name: Pyrazine-2,3-dicarboxylic acid, Name is Pyrazine-2,3-dicarboxylic acid, molecular formula is C6H4N2O4, molecular weight is 168.11, MDL number is MFCD00006131, category is Pyrazines. Now introduce a scientific discovery about this category.

A Redox-Active Heterobimetallic N-Heterocyclic Carbene Based on a Bis(imino)pyrazine Ligand Scaffold

A new redox-active N-heterocyclic carbene (NHC) architecture is obtained using N-methylated pyrazinediimine iron complexes as precursors. The new species exhibit strong pi-accepting/sigma-donating properties and are able to ligate two metal centres simultaneously. The redox activity was demonstrated by the reversible chemical oxidation of a heterobimetallic Fe-0/Rh(I)example, which affords an isolable ligand-based radical cation. The reversible redox process was then applied in the catalytic hydrosilylation of 4,4 ‘-difluorobenzophenone, where the reaction rate could be reversibly controlled as a function of the catalyst oxidation state. The new NHC exhibits high electrophilicity and nucleophilicity, which was demonstrated in the reversible activation of alcohols and amines. The electronic structure of the resulting complexes was investigated through various spectroscopic and computational methods.

If you are interested in 89-01-0, you can contact me at any time and look forward to more communication. Name: Pyrazine-2,3-dicarboxylic acid.

Application of 89-01-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a article, author is Contreras-Torres, Flavio F., introduce new discover of the category.

Dispersion-Corrected Density Functional Theory Study of the Noncovalent Complexes Formed with Imidazo[1,2-a]pyrazines Adsorbed onto Silver Clusters

Imidazo[1,2-a]pyrazines are cyclic amidine type compounds composed of alpha-amino acid residues. A full structural identification of these molecules constitutes an analytical challenge, especially when imidazo, [1, 2-a] pyrazines are obtained from physical processes (e.g., sublimation and pyrolysis of amino acids). A valuable source of molecular inforination can be obtained from absorption spectroscopies and related techniques encoinpassing the use of metallic substrates. The aim of this study is to provide new knowledge and insights into the noncovalent intermolecular interactions between imidazo[1,2-a]pyrazines and two Ag-n (n = 4 and 20) clusters using density functional theory (DFT) methods. Semiempirical DFT dispersion (DFT-D) corrections were addressed using Grimme’s dispersion (GD2) and Austin- Petersson Frisch (APF) functionals in conjunction with the 6-31+G(d,p) + LANL2DZ mixed basis set. These DFT-D methods describe strong interactions; besides, in all cases, the APF dispersion (APF-D) energies of interaction appear to be consistently overestimated. In comparison with B3LYP calculations, the mean values for the difference in the energies of interaction calculated are 2.25 (GD2) and 6.24 (APF-D) kcal mol(-1) for Ag-4(-) molecules, and 2.30 (GD2) land 8.53 (APF-D) kcal mol(-1) for Ag-20-molecules. The effect of applying GD2 and APF-D corrections to the noncovalent complexes is nuanced in the intermolecular distances calculated, mainly in the Ag center dot center dot center dot N(amidine) bonding, which appears to play the most important role for the adsorptive process. Selective enhancement and considerable red shifts for Raman vibrations suggest strong interactions, whereas a charge redistribution involving the metallic substrate and the absorbate leads to a significant rearrangement of frontier molecular orbitals mainly in the Ag-20-molecule complexes. Finally, time-dependent DFT calculations were carried out to access the orbital contributions to each of the transitions observed in the absorption spectrum. The corresponding UV-vis spectra involve transitions in the visible region at around 400 and 550 nm for the Ag-4-molecule and the Ag-20-molecule complexes, respectively.

Application of 89-01-0, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 89-01-0 is helpful to your research.

Chemistry, like all the natural sciences, COA of Formula: C6H4N2O4, begins with the direct observation of nature¡ª in this case, of matter.89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a document, author is Pakyapan, Bilge, introduce the new discover.

Synthesis and catalytic applications of Ru and Ir complexes containing N,O-chelating ligand

A series of monometallic complexes (Ru1-3, Ir-1(-3)) which have N,O-chelating ligand (pyrazine-2carboxylate (1), pyridine-2-carboxylate (2), quinoline carboxylate(3) and bimetallic complexes (Ru-4,Ru-5, Ir-4(,5)) bridged by pyrazine-2,3- dicarboxylate (4) and imidazole-4,5-dicarboxylate(5) were synthesized and characterized by H-1-, C-13 NMR, FT-IR, and elemental analysis. The crystal structure of Ir-2 was determined by X-ray crystallography. The complexes (Ru1-5, Ir1-5) were applied to investigate the electronic and steric effect of ligand in their catalytic activities in transfer hydrogenation and alpha(alpha)-alkylation reaction of ketones with alcohols. The activities of iridium complexes (Ir1-5) were much more efficient than ruthenium complexes (Ru1-5). The highest activity for both reactions was observed for the complex (Ir2 ) with pyridine-2-carboxylate. The Ir hydride species was monitored for both reactions. (C) 2020 Elsevier B.V. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 89-01-0. COA of Formula: C6H4N2O4.

Reference of 89-01-0, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a article, author is Gao, Zili, introduce new discover of the category.

Effect of alkaline extraction pH on structure properties, solubility, and beany flavor of yellow pea protein isolate

In the current study, the impact of alkaline extraction pH (8.5, 9.0, and 9.5) on chemical composition, molecular structure, solubility and aromatic profile of PPI was investigated by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), the quantification of free sulfhydryl group and disulfide bond contents, size exclusion chromatography with multi-angle static light scattering and refractive index (SEC-MALS-RI), circular dichroism (CD) spectroscopy, and headspace solid phase micro extraction gas chromatography-mass spectroscopy (HS-SPME-GC-MS). We found that protein recovery yield increased from 49.20% to 57.56% as the alkaline extraction pH increased from 8.5 to 9.5. However, increasing the extraction pH promoted the formation of protein aggregates which decreased the percent protein solubility although there was no influence on protein secondary structure. PPI extracted at pH 9.0 possessed the lowest beany flavor as revealed by the selected six beany flavor markers including alcohols, aldehydes, ketones and pyrazine. The lowest lipoxygenase activity at pH 9.0 may contribute to the least beany flavor in PPI. Therefore, pH 9.0 was found to be the optimal condition for preparing premium PPI in terms of yield, functionality, and aromatic profile using alkaline extraction-isoelectric precipitation process. The findings could have fundamental implications for the preparation and utilization of pea proteins in food applications.

Reference of 89-01-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 89-01-0.

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, molecular formula is , belongs to Pyrazines compound. In a document, author is Yu, Ling, Recommanded Product: Pyrazine-2,3-dicarboxylic acid.

Pyrido[2,3-b]pyrazine-based full-color fluoresent materials for high-performance OLEDs

High photoluminescence quantum efficiency (PLQY) and simple molecular structure in a full-color emitting material system are two crucial issues for cost-effective multicolor display applications. Herein, a new tailor-made fluorescent core (pyrido[2,3-b]pyrazine) is designed and synthesized. Through systematically fine-tuning the band gap, the versatile pyrido[2,3-b]pyrazine family exhibits a wide range of emissions spanning the entire visible region from blue to red. By reasonable choice of donor units, two thermally activated delayed fluorescence (TADF) molecules are obtained and the resulting OLEDs exhibit a yellow emission and an orange emission with high EQEs of up to 20.0% and 15.4%, respectively.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 89-01-0, in my other articles. Recommanded Product: Pyrazine-2,3-dicarboxylic acid.

Reference of 89-01-0, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 89-01-0, Name is Pyrazine-2,3-dicarboxylic acid, SMILES is O=C(C1=NC=CN=C1C(O)=O)O, belongs to Pyrazines compound. In a article, author is Nishiyama, Yoshitake, introduce new discover of the category.

Facile Synthesis of Tetraarylpyrazines by Sequential Cross-coupling Approach

A facile synthetic method for unsymmetric tetraarylpyrazines by sequential cross-couplings is disclosed. This 5-step synthesis was achieved from 2-amino-3,5-dibromo-6-chloropyrazine through four-fold cross-coupling and diazotization. Dibenzo-fused quinoxaline synthesis was also accomplished by further intramolecular coupling.

Reference of 89-01-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 89-01-0.