Category: 723286-67-7

Reference of 723286-67-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 723286-67-7, name is Ethyl 1,2,4-Triazolo[4,3-a]pyrazine-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows.

A mixture of 380 mg of ethyl [1, 2,4] triazolo [4,3-a] pyrazine-3-carboxylate from Step B and 50 mg of 10% palladium on carbon in 10 ML of ethyl acetate and 10 mL of ethanol was stirred under an atmosphere of hydrogen for 18 h. The mixture was filtered through a pad of Celite and the filtrate concentrated to give the title compound as a solid. LC/MS 169 (M+1).

The chemical industry reduces the impact on the environment during synthesis Ethyl 1,2,4-Triazolo[4,3-a]pyrazine-3-carboxylate. I believe this compound will play a more active role in future production and life.

Reference:
Patent; MERCK & CO., INC.; WO2004/58266; (2004); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

These common heterocyclic compound, 723286-67-7, name is Ethyl 1,2,4-Triazolo[4,3-a]pyrazine-3-carboxylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 723286-67-7

A mixture of 380 mg of ethyl [1, 2,4] triazolo [4,3-a] pyrazine-3-carboxylate from Step B and 50 mg of 10% palladium on carbon in 10 ML of ethyl acetate and 10 mL of ethanol was stirred under an atmosphere of hydrogen for 18 h. The mixture was filtered through a pad of Celite and the filtrate concentrated to give the title compound as a solid. LC/MS 169 (M+1).

The synthetic route of Ethyl 1,2,4-Triazolo[4,3-a]pyrazine-3-carboxylate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; MERCK & CO., INC.; WO2004/58266; (2004); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Some common heterocyclic compound, 723286-67-7, name is Ethyl 1,2,4-Triazolo[4,3-a]pyrazine-3-carboxylate, molecular formula is C8H8N4O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Product Details of 723286-67-7

A mixture of 170 mg of ethyl [1, 2,4] triazolo [4, 3-a] pyrazine-3-carboxylate from Example 8, Step B and 3 mL of tert-butylamine was heated in a sealed tube at reflux for 8 h. Concentration followed by flash chromatography (silica gel, eluting sequentially with 100% ethyl acetate and 10% methanol/dichloromethane) gave the title compound as a viscous oil. LC/MS 219.9 (M+1).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 723286-67-7, its application will become more common.