Extracurricular laboratory: Synthetic route of 66490-61-7

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 66490-61-7.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 66490-61-7, name is 3,5,6-Tribromopyrazin-2-amine, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C4H2Br3N3

EXAMPLE 2 Preparation of 3-Amino-5,6-dibromopyrazinethiol Aminotribromopyrazine was prepared, by the same procedure reported for the trichloro analog, from tetrabromopyrazine. Using the same procedure as above, 30 g. of aminotribromopyrazine, and 24 g. of sodium sulfide nonohydrate in 500 IPA gave 13.5 g. (53% yield) of the desired compound. Anal. Calcd. for C4 H3 Br2 N3 S: C, 16.86; H, 1.06; N, 14.74. Found: C, 17.55; H, 1.21; N, 14.89.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 66490-61-7.

Reference:
Patent; The Dow Chemical Company; US4075207; (1978); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Simple exploration of 3,5,6-Tribromopyrazin-2-amine

The synthetic route of 3,5,6-Tribromopyrazin-2-amine has been constantly updated, and we look forward to future research findings.

Related Products of 66490-61-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 66490-61-7, name is 3,5,6-Tribromopyrazin-2-amine belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.

General procedure: [0268] In a mixture of 3,5,6-tribromopyrazin-2-amine (146 mg, 0.5 mmol), triethylamine (202 mg, 2 mmol), and catalytic amount of DMAP (5 mol %) in dry CH2CI2 (5 mL) was added 3- fluorobenzoylchloride (176 mg, 1 mmol) at room temperature. The mixture was stirred at room temperature overnight, and concentrated under reduced pressure. The residue was then dissolved in MeOH (5 mL) and K2CO3 (100 mg) was added. The mixture was stirred at 60 C for 1 h. The mixture was then reduced down and the product purified via silica chromatography (ethyl acetate:hexanes).

The synthetic route of 3,5,6-Tribromopyrazin-2-amine has been constantly updated, and we look forward to future research findings.