Category: 32974-92-8

Related Products of 32974-92-8,Some common heterocyclic compound, 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, molecular formula is C8H10N2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

(1) Dissolving 10 mmol of 2-acetyl-3-ethylpyrazine in 20 mL of methanol,Stir at 60 C for 15 min,Will then20 mL, 10 mmol of thiosemicarbazide in methanol was added dropwise to the above solution.After refluxing at 60 C for 12 h,After cooling to room temperature, pour into the beaker and evaporate.The pale yellow crystal obtained above was filtered and washed with methanol three times.Get ligand (L1);

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1-(3-Ethylpyrazin-2-yl)ethanone, its application will become more common.

Reference:
Patent; Guangxi Normal University; Yang Feng; Yu Ping; Wang Jun; Liang Hong; (14 pag.)CN108912149; (2018); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, A new synthetic method of this compound is introduced below., Product Details of 32974-92-8

(1) Dissolve 10 mmol of 2-acetyl-3-ethylpyrazine in 20 mL of methanol and stir at 60 C for 15 min.Then, 20 mL, 10 mmol of 4,4-dimethyl-3-aminourea methanol solution was added dropwise to the above solution, and refluxed at 60 C.After the reaction was stirred for 12 h, it was cooled to room temperature, poured into a beaker and evaporated. The obtained pale yellow crystals were filtered and washed with methanol.Times, get the ligand (L4);

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Guangxi Normal University; Yang Feng; Yu Ping; Wang Jun; Liang Hong; (14 pag.)CN108912149; (2018); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 32974-92-8 as follows. Recommanded Product: 1-(3-Ethylpyrazin-2-yl)ethanone

Example 1882-(N-t-butylbenzyl)aminoethyl-2-(3-ethyl)-pyrazylketone 8658 2-acetyl-3-ethylpyrazine (151 mg), benzyl-t-butyl amine (149 mg), and paraformaldehyde (40 mg) were reacted in dioxane (0.2 ml) at 130 C. for 2 hours.NMR (CDCl3) 1.1 (m, 9H), 2.7 (m, 1H), 3.1 (m, 4H), 3.7 (m, 2H), 7-7.1 (m, 1H), 8.5-8.6 (m, 1H)TG 42 (3 mumol) 22 (10 mumol) 10 (30 mumol)SOCE 0 (10 mumol) 0 (30 mumol) 20 (100 mumol)IICR 50 (10 mumol) 90 (30 mumol) 100 (100 mumol)

According to the analysis of related databases, 32974-92-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Japan Science and Technology Agency; US2012/277423; (2012); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Synthetic Route of 32974-92-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.

Example 2602-(N-bis-hydroxyethyl)aminoethyl-3-ethyl-2-pyrazylketone 8733 2-acetyl-3-ethylpyrazine (148 mg), diethanol amine (119 mg), and paraformaldehyde (40 mg) were reacted at 130 C. for 2 hours.NMR (CDCl3) 1.31 (t, 3H), 2.75 (m, 43H), 3.25 (m, 2H), 3.71 (m, 2H), 3.80 (M, 2H), 4.0 (m, 2H), 8.2 (s, 1H), 8.25 (s, 1H)TG 76.3 (3 mumol) 45.2 (10 mumol) 10.2 (30 mumol)SOCE 0 (10 mumol) 0 (30 mumol) 0 (100 mumol)IICR 20 (10 mumol) 0 (30 mumol) 20 (100 mumol)

The synthetic route of 1-(3-Ethylpyrazin-2-yl)ethanone has been constantly updated, and we look forward to future research findings.

Related Products of 32974-92-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.

(1) Dissolving 10 mmol of 2-acetyl-3-ethylpyrazine in 20 mL of methanol,Stir at 60 C for 15 min,Then 20mL, 10mmol4-methylthiosemicarbazideMethanol solution is added dropwiseInto the above solution,After refluxing at 60 C for 12 h,After cooling to room temperature, pour into the beaker and evaporate.The pale yellow crystal obtained above was filtered and washed with methanol three times.Get ligand (L2);

The synthetic route of 1-(3-Ethylpyrazin-2-yl)ethanone has been constantly updated, and we look forward to future research findings.

32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, belongs to pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C8H10N2O

General procedure: The ligands L1-L4 were synthesized by reflux method. Shown in Scheme 1, 5mM of 2-Acetyl-3-ethylpyrazine and thiosemicarbazides (L1), 5mM of 2-Acetyl-3-ethylpyrazine and 4-methylthiosemicarbazide (L2), 5mM of 2-Acetyl-3-ethylpyrazine and 4-phenylthiosemicarbazide (L3), and 5mM of 2-Acetyl-3-ethylpyrazine and 3-pyrrolethiosemicarbazide (L4) were stirred in CH3OH for 3 h at 65C. The ligands were precipitated and filtered. L1-L4 were characterized by infrared spectroscopy, electrospray ionization mass spectrometry (ESI-MS), 1H NMR, and 13C NMR (Supplementary Figs S4- S31).

The synthetic route of 32974-92-8 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Khan, Muhammad Hamid; Cai, Meiling; Li, Shanhe; Zhang, Zhenlei; Zhang, Juzheng; Wen, Xiaoan; Sun, Hongbin; Liang, Hong; Yang, Feng; European Journal of Medicinal Chemistry; vol. 182; (2019);,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Adding a certain compound to certain chemical reactions, such as: 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, belongs to Pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 32974-92-8, Product Details of 32974-92-8

(1) 10 mmol of 2-acetyl-3-ethylpyrazine was dissolved in 20 ml of methanol,Stirring at 60 C for 15 min to prepare a solution;(2) taking 10 mmol of 3-pyrrol-3-thiosemicarbazide dissolved in 20 ml of methanol,The solution prepared in the step (1) is dropwise added to a methanol solution containing 3-pyrrol-3-thiosemicarbazide, and the reaction mixture is stirred under reflux at 60 C for 24 hours to obtain a pale yellow precipitate.After the reaction, it was cooled to room temperature and poured into a beaker to evaporate.The resulting precipitate was filtered and washed 3 times with absolute ethanol.After drying, the ligand L4 is obtained;

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-(3-Ethylpyrazin-2-yl)ethanone, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Guangxi Normal University; Yang Feng; Cai Meiling; Li Wenjuan; Liang Hong; (15 pag.)CN109796497; (2019); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Synthetic Route of 32974-92-8, These common heterocyclic compound, 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Previous method was used for preparing Ligands (L1-L7). Ethanol(10 mL, 1 mM) solution of piperidylthiosemicarbazide was added to corresponding aldehyde or ketone (one mole equivalent) and 5 drops of acetic acid glacial, with stirred and refluxed for 4 h. The precipitate was filtered with filter paper and rinsed with Cold ethanol. A vacuum desiccator was applied to dry the precipitate.

Statistics shows that 1-(3-Ethylpyrazin-2-yl)ethanone is playing an increasingly important role. we look forward to future research findings about 32974-92-8.

Reference:
Article; Qi, Jinxu; Yao, Qian; Qian, Kun; Tian, Liang; Cheng, Zhen; Wang, Yihong; Journal of Inorganic Biochemistry; vol. 186; (2018); p. 42 – 50;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Application of 32974-92-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, This compound has unique chemical properties. The synthetic route is as follows.

General procedure: The ligands L1-L4 were synthesized by reflux method. Shown in Scheme 1, 5mM of 2-Acetyl-3-ethylpyrazine and thiosemicarbazides (L1), 5mM of 2-Acetyl-3-ethylpyrazine and 4-methylthiosemicarbazide (L2), 5mM of 2-Acetyl-3-ethylpyrazine and 4-phenylthiosemicarbazide (L3), and 5mM of 2-Acetyl-3-ethylpyrazine and 3-pyrrolethiosemicarbazide (L4) were stirred in CH3OH for 3 h at 65C. The ligands were precipitated and filtered. L1-L4 were characterized by infrared spectroscopy, electrospray ionization mass spectrometry (ESI-MS), 1H NMR, and 13C NMR (Supplementary Figs S4- S31).

The chemical industry reduces the impact on the environment during synthesis 1-(3-Ethylpyrazin-2-yl)ethanone. I believe this compound will play a more active role in future production and life.

Reference:
Article; Khan, Muhammad Hamid; Cai, Meiling; Li, Shanhe; Zhang, Zhenlei; Zhang, Juzheng; Wen, Xiaoan; Sun, Hongbin; Liang, Hong; Yang, Feng; European Journal of Medicinal Chemistry; vol. 182; (2019);,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Application of 32974-92-8, The chemical industry reduces the impact on the environment during synthesis 32974-92-8, name is 1-(3-Ethylpyrazin-2-yl)ethanone, I believe this compound will play a more active role in future production and life.

(1) 10 mmol of 2-acetyl-3-ethylpyrazine was dissolved in 20 ml of methanol,Stirring at 60 C for 15 min to prepare a solution;(2) taking 10 mmol of 4-methylthiosemicarbazide dissolved in 20 ml of methanol,The solution prepared in the step (1) is dropwise added to a methanol solution containing 4-methylthiosemicarbazide, and the reaction mixture is stirred under reflux at 60 C for 24 hours to obtain a pale yellow precipitate.After the reaction, the mixture was cooled to room temperature, poured into a beaker and evaporated, and the resulting precipitate was filtered.Wash 3 times with absolute ethanol,After drying, the ligand L2 is obtained;Yield: 86.7%,

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-(3-Ethylpyrazin-2-yl)ethanone, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Guangxi Normal University; Yang Feng; Cai Meiling; Li Wenjuan; Liang Hong; (15 pag.)CN109796497; (2019); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem