Category: 2882-21-5

Related Products of 2882-21-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2882-21-5, name is 2-Methoxy-6-methylpyrazine belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below.

To a solution of 2-methoxy-6-methylpyrazine (21.3 g, 171.6 mmol) in AcOH (150 mL) was added NaB02-H202-3H20 (31.7 g, 205.9 mmol). The mixture was stirred at 80C for 16 hours. The mixture was cocentrated in vacuo and diluted with 2 M aq. NaOH (300 mL). The mixture was extracted with EtOAc (200 mL chi 4). The organic layer was washed with brine (100 mL), dried over Na2S04 and concentrated in vacuo to give 3-methoxy-5-methylpyrazine 1-oxide (14.4 g, 60% yield).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methoxy-6-methylpyrazine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; H. LUNDBECK A/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; LANGGARD, Morten; JESSING, Mikkel; VITAL, Paulo, Jorge, Vieira; JUHL, Karsten; (157 pag.)WO2018/78038; (2018); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2882-21-5, name is 2-Methoxy-6-methylpyrazine, A new synthetic method of this compound is introduced below., SDS of cas: 2882-21-5

To a solution of 2-methoxy-6-methylpyrazine (21.3 g, 171.6 mmol) in AcOH (150 mL) was added NaB02-H202-3H20 (31.7 g, 205.9 mmol). The mixture was stirred at 80C for 16 hours. The mixture was cocentrated in vacuo and diluted with 2 M aq. NaOH (300 mL). The mixture was extracted with EtOAc (200 mL chi 4). The organic layer was washed with brine (100 mL), dried over Na2SC>4 and concentrated in vacuo to give 3-methoxy-5-methylpyrazine 1-oxide (14.4 g, 60% yield).

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; H. LUNDBECK A/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; LANGGARD, Morten; JESSING, Mikkel; VITAL, Paulo, Jorge, Vieira; JUHL, Karsten; (159 pag.)WO2018/78042; (2018); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Electric Literature of 2882-21-5, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2882-21-5 as follows.

To a solution of 2-methoxy-6-methylpyrazine (21.3 g, 171.6 mmol) mAcOH (150 mL)was added NaBO2 H202 3H20 (31.7 g, 205.9 mmol). The mixture was stirred at 80C for 16 hours. The mixture was cocentrated in vacuo and diluted with 2 M aq. NaOH (300 mL). The mixture was extracted with EtOAc (200 mL x 4). The organic layer was washed with brine (100 mL), dried over Na2SO4 and concentrated in vacuo to give 3-methoxy-5-methylpyrazine1-oxide (14.4 g, 60% yield).

According to the analysis of related databases, 2882-21-5, the application of this compound in the production field has become more and more popular.