Category: 25680-54-0

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 25680-54-0, name is 3-Ethylpyrazin-2(1H)-one, A new synthetic method of this compound is introduced below., Safety of 3-Ethylpyrazin-2(1H)-one

2. 2-Iodo-3-ethylpyrazine This was prepared from 2-hydroxy-3-ethyl-pyrazine by the procedure of Hirschberg and Spoerri, J. Org. Chem., 1961, 1907.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Merck Sharp & Dohme Limited; US5260293; (1993); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25680-54-0, name is 3-Ethylpyrazin-2(1H)-one, This compound has unique chemical properties. The synthetic route is as follows., Formula: C6H8N2O

(iii) 3-Ethyl-2-hydroxypyrazine (5 g) was heated with phosphorus oxychloride (15 ml) at reflux for 3 hours. The reaction was allowed to cool to ambient temperature and then poured onto 200 g of crushed ice. The mixture was extracted with dichloromethane (3*150 ml) and the combined extracts were dried (MgSO4). Volatile material was removed by evaporation to give a brown oil. The oil was purified by chromatography on silica gel, eluding with dichloromethane, to give 2-chloro-3-ethylpyrazine as a colourless oil (5.64 g, 98%); 1 H NMR (d6 -DMSO, 200 MHz): 1.25 (t,3H), 2.93 (q,2H), 8.36 (d,1H), 8.59 (d,1H); mass spectrum (+ve CI): 143 (M+H)+.

According to the analysis of related databases, 25680-54-0, the application of this compound in the production field has become more and more popular.