Category: 2150-55-2

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Determination of 2-iminothiazolidine-4-carboxylic acid, published in 1965, which mentions a compound: 2150-55-2, mainly applied to , Electric Literature of C4H6N2O2S.

Procedures are described for determination of 2-iminothiazolidine-4-carboxylic acid, using diazotized sulfanilic acid or the mercury-diphenylthiocarbazone reaction. The compound should first be separated from interfering substances such as are found in urine. Paper electrophoresis, ion displacement, or chromatography suffice for this purpose.

In some applications, this compound(2150-55-2)Electric Literature of C4H6N2O2S is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Name: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid, is researched, Molecular C4H6N2O2S, CAS is 2150-55-2, about 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation.

In this study, the ability of either 2-iminothiazolidine-4-carboxylic acid (2-ICA), glutamate, proline or NMDA (N-methyl-D-aspartate) injected i.c.v. to produce hippocampal lesions sensitive to glutamate antagonists was compared in mice. Hippocampal CA1 damage was observed 5-days following either a seizure (3.2 μmol) or subseizure (1.0 μmol) dose of 2-ICA. Glutamate (3.2 μmol) or proline (10 μmol) also produced hippocampal damage; glutamate damage was primarily to the CA1 subfield, whereas proline damaged neurons throughout the entire hippocampal formation. NMDA (3.2 nmol) caused seizure activity in all animals with a 50% lethality. No hippocampal damage was observed in surviving mice. Neither MK-801 (dizocilpine maleate) nor CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) pretreatment prevented hippocampal lesions produced by 2-ICA. In contrast, MK-801 significantly reduced the frequency of mice displaying glutamate hippocampal lesions, but failed to block seizures produced by glutamate. MK-801 also protected neurons in the CA2-3 zone and the dentate gyrus, but not in the CA1 region of proline-injected mice. Finally, pretreatment with the mixed metabotropic glutamate receptor (mGluR)1/mGluR2 antagonist-agonist (S)-4-carboxy-3-hydroxyphenylglycine (CHPG) prevented hippocampal damage produced by the mGluR 1 agonist (RS)-3,5-dihydroxyphenylglycine (DHPG), but did not protect against 2-ICA hippocampal lesions. These results show that 2-ICA hippocampal CA1 damage is not mediated through ionotropic or metabotropic glutamate receptors. 2-ICA hippocampal damage may represent a neurotoxicity that is distinct from excitotoxic-mediated cell death.

As far as I know, this compound(2150-55-2)Name: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Zwitterion structure and acylative ring-opening reactions of 2-aminothiazoline-4-carboxylic acid, published in 1962, which mentions a compound: 2150-55-2, mainly applied to , Related Products of 2150-55-2.

pKA values (pK1 2.03, pK2 8.48), variation of optical rotation with pH and other phys. properties indicate that 2-aminothiazoline-4-carboxylic acid is a zwitterion in solution and in the solid state anti that pK2 can be ascribed to ionization from the ring nitrogen. Acylation of 2-aminothiazoline-4-carboxylic acid in aqueous medium is accompanied by ring opening. With Ac2O N’, S-diacetyl-N-carbamoylcysteine is obtained and with BzCl S-benzoyl-N-carbamylcysteine and 2-imino-3-benzoylthiazolidine-4-carboxylic acid are obtained. Structures of the acylated products were proven by chem. methods and by interpretation of nuclear magnetic resonance data

As far as I know, this compound(2150-55-2)Related Products of 2150-55-2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 2150-55-2, is researched, Molecular C4H6N2O2S, about Isolation and genetic improvement of Pseudomonas sp. strain HUT-78, capable of enzymatic production of L-cysteine from DL-2-amino-Δ2-thiazoline-4-carboxylic acid, the main research direction is cysteine production Pseudomonas fermentation mutagenesis genetic engineering; aminothiazolinecarboxylate hydrolase carbamoylcysteine amidohydrolase Pseudomonas.Reference of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid.

Microorganisms able to bioconvert DL-2-amino-Δ2-thiazoline-4-carboxylic acid (DL-ATC) into L-cysteine were originally isolated from 10 soil samples with DL-ATC as the sole nitrogen source. Ninety-seven L-cysteine-producing bacterial strains were screened out and obtained in pure culture. Among them, a strain, designated as HUT-78, was selected as the best producer, with a molar bioconversion rate of 60%. Based on the 16S rRNA gene sequence anal., this isolate was placed within the genus Pseudomonas. A novel mutant of this strain with a significantly reduced activity of L-cysteine desulfhydrase, a L-cysteine-decomposing enzyme, was derived by UV-mutagenesis. This mutant, designated as mHUT-78, exhibited a 42% increase in L-cysteine producing activity. Moreover, the bioconversion reactions in both the parent and the mutant strain were significantly accelerated by co-overexpression of the two key enzymes, AtcB and AtcC, involved in the bioconversion reaction.

As far as I know, this compound(2150-55-2)Reference of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Simultaneous oxidative reaction crystallization of L-cystine from L-cysteine with enzyme reactions from DL-amino-thiazoline-carboxylic acid》. Authors are Kumon, S.; Shirota, T.; Kitahara, T..The article about the compound:2-Amino-4,5-dihydrothiazole-4-carboxylic acidcas:2150-55-2,SMILESS:O=C(C1N=C(N)SC1)O).COA of Formula: C4H6N2O2S. Through the article, more information about this compound (cas:2150-55-2) is conveyed.

A novel system for oxidative reaction crystallization of L-cystine (CySSCy) from L-cysteine (CySH) obtained by simultaneous enzyme reaction was studied. L-cysteine was produced from DL-amino-thiazoline-carboxylic acid (ATC) by enzymes in the same cell grown beforehand. Generally, the processes involving oxidation after enzyme reactions are time consuming and yield small size CySSCy crystals. In the present investigation oxygen was fed simultaneously along with the enzyme reaction in such a way that it was matched both with the production and oxidation rates of CySH yielding CySSCy at an optimum rate, thus minimizing the level of dissolved oxygen which suppresses the activities of the oxygen-sensitive enzymes. As a result, the overall reaction time was reduced and large size CySSCy crystals were obtained, while improving the enzyme reaction yield.

As far as I know, this compound(2150-55-2)COA of Formula: C4H6N2O2S can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

HPLC of Formula: 2150-55-2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid, is researched, Molecular C4H6N2O2S, CAS is 2150-55-2, about Progress on enzymatic synthesis of L-cysteine from DL-ATC by Pseudomonas sp.. Author is Wu, Min; Chen, Wei-qing; Wang, Pu; He, Jun-yao.

A review. The microbial transformation method for L-cysteine production shows evident advantages, because of its short cycle time, low cost, high region and stereoselectivity, easy control of reaction condition, and environment-friendly. Recently, studies on the bioconversion of DL-2-amino-Δ2-thiazoline-4-carboxylic acid (DL-ATC) to L-cysteine by intracellular enzymes were reported. The research progresses on L-cysteine production by microbial bioconversion, especially Pseudomonas sp., or its crude enzyme extract are summarized. The applications of immobilization technol. in the biotransformation of DL-ATC to L-cysteine are introduced. The genetically engineered bacteria and the study progresses of L-cysteine desulfhydrase were also discussed.

As far as I know, this compound(2150-55-2)HPLC of Formula: 2150-55-2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Application In Synthesis of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid, is researched, Molecular C4H6N2O2S, CAS is 2150-55-2, about Enzymatic production of cystine in commercial plant.

For the enzymic production of cystine in a com. plant, the improvement of reaction process, the purification procedure, and the removal process of hydrogen sulfide were studied. Fed-batch process was adapted to the enzymic reaction and optimized. In the purification process, contaminating Fe ion was excluded from cystine products by adding chelating agent and the co-produced hydrogen sulfide was removed by an oxidation method. An improved process was realized in the industrial plant.

As far as I know, this compound(2150-55-2)Application In Synthesis of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Nagasawa, Toru; Yamada, Hideaki published an article about the compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid( cas:2150-55-2,SMILESS:O=C(C1N=C(N)SC1)O ).Related Products of 2150-55-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:2150-55-2) through the article.

A review with 21 references on the microbial conversion of DL-2-amino-Δ2-thiazoline-4-carboxylic acid  [2150-55-2] to L-cysteine  [52-90-4] and cystine  [56-89-3]; the enzymic synthesis of L-cysteine from β-chloro-L-alanine  [2731-73-9] and Na2S by pyridoxal phosphate-dependent enzymes; and the synthesis of D-cysteine  [921-01-7] by β-chloro-D-alanine dehydrochlorinase  [78990-65-5].

As far as I know, this compound(2150-55-2)Related Products of 2150-55-2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid(SMILESS: O=C(C1N=C(N)SC1)O,cas:2150-55-2) is researched.Related Products of 2150-55-2. The article 《Development of magnetic carbon nanotubes for dispersive micro solid phase extraction of the cyanide metabolite, 2-aminothiazoline-4-carboxylic acid, in biological samples》 in relation to this compound, is published in Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. Let’s take a look at the latest research on this compound (cas:2150-55-2).

2-Aminothiazoline-4-carboxylic acid (ATCA) is a minor metabolite of cyanide and is suggested to be a promising biomarker for cyanide exposure due to its specificity to cyanide metabolism and its excellent short- and long-term stability during storage. In this study, magnetic carbon nanotubes, including magnetic multi-walled carbon nanotubes (Mag-MWCNT) and magnetic single-walled carbon nanotubes (Mag-SWCNT) were synthesized as a novel sorbent for dispersive micro solid phase extraction (d-μSPE) to extract ATCA from biol. matrixes. ATCA spiked deionized water samples with the addition of the isotopic internal standard (ATCA – 13C, 15N) were subjected to Mag-CNT/d-μSPE to confirm extraction efficiency of this new technique. The extracted ATCA was derivatized and quantitated using gas chromatog./mass spectrometry (GC/MS) anal. The extraction parameters were optimized and a detection limits of 15 and 25 ng/mL were obtained for synthetic urine and bovine blood resp. with a linear dynamic range of 30-1000 ng/mL. The optimized Mag-CNT/d-μSPE method facilitated efficient extraction of ATCA using 2 mg of Mag-MWCNT with a 10-min extraction time. The current assay was also found to be effective for the extraction of ATCA with average recoveries of 97.7% and 96.5% from synthetic urine and bovine blood resp. The approach of using Mag-CNT to facilitate d-μSPE offered a novel alternative to extract ATCA from complex biol. matrixes.

As far as I know, this compound(2150-55-2)Related Products of 2150-55-2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem

Jackson, Randy; Petrikovics, Ilona; Lai, Edward P. C.; Yu, Jorn C. C. published an article about the compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid( cas:2150-55-2,SMILESS:O=C(C1N=C(N)SC1)O ).Electric Literature of C4H6N2O2S. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:2150-55-2) through the article.

In forensic casework, a stable and quantifiable marker is desirable for the determination of cyanide poisoning in biol. fluids. 2-Aminothiazoline-4-carboxylic acid (ATCA) is a chem. stable urinary metabolite of cyanide that has been considered to be a reliable biol. marker for cyanide exposure. However, endogenous ATCA is always present in low quantity originating from either dietary intake of cyanide or from normal metabolism of amino acids. A selective and sensitive anal. method is needed to determine the endogenous level of ATCA in order to identify cyanide poisoning. The objective of this research was to prepare molecularly imprinted polymers (MIPs) on the surface of a silica stir bar for molecularly imprinted stir bar sorption extraction (MISBSE). Under optimal extraction conditions, the MISBSE could selectively preconc. ATCA from urine samples. The binding capacity of one MISBSE stir bar for ATCA was determined to be 35 ± 3 ng (n = 3). Combining MISBSE with electrospray ionization tandem mass spectrometry (ESI/MS/MS), ATCA was detected without derivatization at the 400 ng/mL concentration level. This new strategy of MISBSE-ESI/MS/MS enhanced the selectivity and sensitivity for the detection of ACTA in urine samples.

As far as I know, this compound(2150-55-2)Electric Literature of C4H6N2O2S can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem