Application of 33332-29-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 33332-29-5, name is 2-Amino-5-chloropyrazine belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
2-(6-Chloro-5-cyano-pyridin-3-yl)-pentanoic acid (5-chloro-pyrazin-2-yl)-amide The title product was synthesized following the general procedure E2 starting from 2-(6-Chloro-5-cyano-pyridin-3-yl)-pentanoic acid and 5-Chloro-pyrazin-2-ylamine, (0.10 g, 53%). 1H NMR (400 MHz, Chloroform-d3) delta 9.30 (s, 1H), 8.56 (d, J = 2.3 Hz, 1H), 8.27 (s, 1H), 8.18 (d, J= 2.3 Hz, 1H), 7.92 (s, 1H), 3.59 (t, J= 7.6 Hz, 1H), 2.27 – 2.12 (m, 1H), 1.90-1.80 (m, 1H), 1.46 – 1.19 (m, 2H), 0.98 (t, J= 7.3 Hz, 3H). C15H13N5OCl2, Calculated [350.20], found [M+H+], 2Cl pattern 350-352, RT=1.60 (method f).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Amino-5-chloropyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Siena Biotech S.p.A.; Caramelli, Chiara; Federico, Cesare; Gabellieri, Emanuele; Magnani, Matteo; Micco, Iolanda; EP2878339; (2015); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem