Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 63286-28-2, name is 2-Chloro-3-hydrazinylpyrazine, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 63286-28-2
Step 1 : To a solution of tetrahydrofuran-3-carboxylic acid (1 .0 g, 8.6 mmol) in DMF (15 ml) was added HATU (3.60 g, 9.47 mmol), DIPEA (1 .22 g, 1 .66 ml, 9.47 mmol) and finally 2-chloro-3-hydrazinylpyrazine (1 .37 g, 9.47 mmol). The mixture was stirred for 3 hours at RT. The reaction mixture was poured into sat. aq. Na2CO3 (20 mL) and extracted with ethyl acetate (3×20 mL). The combined organic phases were washed with brine (3×25 mL), dried over MgSO4 and concentrated in vacuo. The crude product was purified by flash chromatography using a gradient of ethyl acetate and heptane to yield 1 .1 g (53%) A/’-(3-chloropyrazin-2-yl)tetrahydrofuran-3- carbohydrazide.
According to the analysis of related databases, 63286-28-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; H. LUNDBECK A/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; JESSING, Mikkel; (126 pag.)WO2016/55618; (2016); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem