Pyrazoles. 6. Synthesis of novel heteroaryl 4-pyrazolyl ketones was written by Hahn, Marianne;Heinisch, gottfried;Holzer, Wolfgang;Schwarz, Helga. And the article was included in Journal of Heterocyclic Chemistry in 1991.Electric Literature of C7H8N2O2 This article mentions the following:
Pyrazolyl ketones I (R = 2-, 3-, 4-pyridinyl, 3-, 4-pyridazinyl, 4-pyrimidinyl, 2-pyrazinyl, 2-, 3-thienyl, 4-bromo-2-thienyl) were prepared by lithiation and condensation of 4-bromopyrazole with RCO2Et or with RCHO (R = 2-, 3-thienyl, 4-bromo-2-thienyl) followed by oxidation In the experiment, the researchers used many compounds, for example, Ethyl pyrazine-2-carboxylate (cas: 6924-68-1Electric Literature of C7H8N2O2).
Ethyl pyrazine-2-carboxylate (cas: 6924-68-1) belongs to pyrazine derivatives. Pyrazines are volatile compounds that are used in the cosmetic, food, flavor, and fragrance industries. Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes.Electric Literature of C7H8N2O2