Metal-catalyzed oxidations. Part 6. Molybdenum-catalyzed olefin epoxidation: ligand effects was written by Thiel, Werner R.;Eppinger, Joerg. And the article was included in Chemistry – A European Journal in 1997.Electric Literature of C7H8N2O2 This article mentions the following:
0E synthesized substituted pyrazolylpyridine ligands to examine their donor properties by spectroscopic (IR, NMR) and computational (AM1) methods. The influence of the substitution patterns on spectroscopic and thermodn. features of molybdenum oxobisperoxo complexes [(L-L)MoO(O2)2] [L-L = 2-(1-alkyl-3-pyrazolyl)pyridine/pyrazine] correlates with the activities of the complexes in catalytic olefin epoxidation reactions. This further proof for the relation between the Lewis acidity and the catalytic activity of epoxidation catalysts supports a reaction mechanism in which the peroxo complex activates the oxidizing agent (H2O2, ROOH) instead of directly transferring an oxygen atom from a 鐣?sup>2-peroxo ligand to the olefin. In the experiment, the researchers used many compounds, for example, Ethyl pyrazine-2-carboxylate (cas: 6924-68-1Electric Literature of C7H8N2O2).
Ethyl pyrazine-2-carboxylate (cas: 6924-68-1) belongs to pyrazine derivatives. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging. Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes.Electric Literature of C7H8N2O2