[2.2](2,6)- and [2.2](2,5)Pyrazinophanes: synthesis and molecular structure was written by Eiermann, Uwe;Krieger, Claus;Neugebauer, Franz A.;Staab, Heinz A.. And the article was included in Chemische Berichte in 1990.Formula: C8H12N2O This article mentions the following:
The title compounds I, ,II and III and their Me derivatives were synthesized either by photolytic sulfur extrusion from the corresponding 2,11-dithia[3.3]pyrazinophanes or by Hofmann 1,6-elimination of the appropriate [(5-methyl-2-pyrazinyl)methyl]trimethylammonium hydroxides followed by dimerization of the generated 2,5-dihydro-2,5-bis(methylene)pyrazines. α-Chlorination of the methylpyrazines with N-chlorosuccinimide gave the required precursors. The results of the x-ray structure determinations for the title compounds which indicate an unequivocal isomer assignment are discussed with regard to steric strain in these mols. The electronic spectra of the title compounds are reported and compared with those of the parent methylpyrazines. In the experiment, the researchers used many compounds, for example, (3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3Formula: C8H12N2O).
(3,5,6-Trimethylpyrazin-2-yl)methanol (cas: 75907-74-3) belongs to pyrazine derivatives. Pyrazinesare six-membered aromatic heterocyclic organic compounds with two nitrogen atoms at 1,4-positions. Pyrazine is a weaker base (pKb = 13.4) than pyridine (pKb = 8.8), pyrimidine (pKb = 12.7). Pyrazine-based skeletons were incorporated into agents targeting a range of ailments. Many derivatives were synthesized and evaluated as potential cancer treatments.Formula: C8H12N2O