Homolytic alkoxycarbonylation reactions in two-phase systems. Part II. Studies on the ethoxycarbonylation of some selected π-deficient N-heteroaromatic systems was written by Heinisch, Gottfried;Loetsch, Gerhard. And the article was included in Tetrahedron in 1986.Related Products of 6924-68-1 This article mentions the following:
Qadical substitution of pyridine, 4-methylpyridine (I; R = H) and pyrazine (II; R = H) with EtO2C• generated from AcCO2Et and H2O2 in an aqueous system gave less than 30% conversion, little selectivity, and significant quantities of disubstitution products. However, in a two-phase system prepared by adding CH2Cl2, I and II (R = H) gave single monosubstitution products, I and II (R = CO2Et) in 53 and 89% yields, resp. With pyridine and quinoline, the two phase system increases conversion to over 90% but disubstitution products continued to dominate. In the experiment, the researchers used many compounds, for example, Ethyl pyrazine-2-carboxylate (cas: 6924-68-1Related Products of 6924-68-1).
Ethyl pyrazine-2-carboxylate (cas: 6924-68-1) belongs to pyrazine derivatives. Pyrazine is an N-heterocyclic moiety, and it can be easily prepared from ethylenediamine and 1,2-diketone, α-hydroxyketone, α-methyl ketone. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging.Related Products of 6924-68-1