Preparation and Biofunctionalization of Multicolor Conjugated Polymer Nanoparticles for Imaging and Detection of Tumor Cells was written by Feng, Liheng;Liu, Libing;Lv, Fengting;Bazan, Guillermo C.;Wang, Shu. And the article was included in Advanced Materials (Weinheim, Germany) in 2014.Formula: C8H4Br2N2 This article mentions the following:
Multicolor conjugated polymer nanoparticles (CPNs) are designed and biofunctionalized with antibody for targeted cell imaging and cell detection. In comparison to single-antibody recognition mode to tumor cells, enhanced specificity for targeted imaging and detection of tumor cells is achieved by binding two antibody functionalized CPNs to one tumor cell. This strategy provides a new platform for designing CPNs useful for targeted imaging, cells detection and other biol. applications. In the experiment, the researchers used many compounds, for example, 5,8-Dibromoquinoxaline (cas: 148231-12-3Formula: C8H4Br2N2).
5,8-Dibromoquinoxaline (cas: 148231-12-3) belongs to pyrazine derivatives. Pyrazine heterocycles and their benzo derivatives possess many interesting properties, including chemical reactivity profiles, and have diverse applications in total synthesis, medicine, chemical biology, materials, dyes, and imaging. Pyrazine-based skeletons were incorporated into agents targeting a range of ailments. Many derivatives were synthesized and evaluated as potential cancer treatments.Formula: C8H4Br2N2