Ionization constants of heterocyclic substances. II. Hydroxy-derivatives of nitrogenous six-membered ring-compounds was written by Albert, Adrien;Phillips, J. N.. And the article was included in Journal of the Chemical Society in 1956.COA of Formula: C7H5N3 This article mentions the following:
Acidic and basic ionization constants were determined potentiometrically and in some cases spectrometrically for 87 hydroxy (and related) derivatives of pyridine, quinoline, isoquinoline, acridine, phenanthridine, pyridazine, pyrimidine, pyrazine, cinnoline, phthalazine, quinazoline, quinoxaline, phenazine, triazine, 1,4,5-triazanaphthalene, and 1,4,6-triazanaphthalene. The tautomeric equilibrium between enol and amide in α and γ-hydroxy derivatives greatly favor the amide form. The preparation of 2-methoxypyrazine, b29 60-1°, and 3-hydroxypyridine methochloride were described. A m.p. of 57° was reported for 2-methyl-1-isoquinolone. In the experiment, the researchers used many compounds, for example, Pyrido[2,3-b]pyrazine (cas: 322-46-3COA of Formula: C7H5N3).
Pyrido[2,3-b]pyrazine (cas: 322-46-3) belongs to pyrazine derivatives. Pyrazine is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes.COA of Formula: C7H5N3