The chemical industry reduces the impact on the environment during synthesis 2727-13-1, name is 3-Amino-6-chloropyrazine-2-carboxylic acid, I believe this compound will play a more active role in future production and life. 2727-13-1
A mixture of 3-amino-6-chloro-pyrazine-2-carboxylic acid (26.0 mg; 0.150 mmol), the amineintermediate IX.3 (100 mg; 0.15 1 mmol), TBTU (53.0 mg; 0.165 mmol), triethylamine (63.2 tl;0.450 mmol) and DMF (5.0 ml) is stirred at r.t. over night. Volatiles are evaporated and the residue is purified by RP-HPLC (C 18; water-ACN-TFA).C26H33C1N705S x C202F3 ESI Mass spectrum: mlz = 590 [M+H]+HPLC analytics: RT = 0.42 mm (HPLC method D)
The chemical industry reduces the impact on the environment during synthesis 2727-13-1. I believe this compound will play a more active role in future production and life.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; HECKEL, Armin; FRATTINI, Sara; HAMPRECHT, Dieter; KLEY, Joerg; WIEDENMAYER, Dieter; (49 pag.)WO2017/28927; (2017); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem