On August 31, 1983, Vekemans, J.; Pollers-Wieers, C.; Hoornaert, G. published an article.SDS of cas: 87486-34-8 The title of the article was A new synthesis of substituted 2(1H)-pyrazinones. And the article contained the following:
The hydrohalides of 2-sec-aminoalkanenitriles on treatment with oxalyl halides in o-Cl2C6H4 at 80-100° give 3,5-dihalo-2(1H)-pyrazinones, e.g. I, of which the 3-halo substituent is easily replaced by nucleophiles. A reaction mechanism for the pyrazinone synthesis is proposed. The experimental process involved the reaction of 3,5-Dibromo-1-methylpyrazin-2(1H)-one(cas: 87486-34-8).SDS of cas: 87486-34-8
The Article related to pyrazinone, aminoalkanenitrile cyclization oxalyl chloride, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.SDS of cas: 87486-34-8