Pyrazine has the elements of symmetry for the point group D2h. It has three mutually perpendicular two-fold axes. 22047-25-2, formula is C6H6N2O, Name is Acetylpyrazine. It also has three mutually perpendicular planes of symmetry. As a result, pyrazine also has a centre of symmetry.. Related Products of 22047-25-2.
Zhu, Meiqing;Wang, Wenliang;Liu, Jia;Na, Risong;Li, Zhenfeng;Wang, Yi research published 《 A novel pyrene-based fluorescent probe for the rapid and efficient detection of Co2+ in HeLa cells and natural water samples》, the research content is summarized as follows. Excessive levels of Co2+ in the environment can cause serious diseases to humans and affect the growth of crops. Therefore, it is necessary to develop effective methods for monitoring Co2+. In the present work, a novel, low-toxic fluorescent probe, PEPA ((E)-N’-(1-(pyrazin-2-yl)ethylidene)pyrene-1-carbohydrazide), for the rapid and efficient detection of Co2+ is synthesized. PEPA shows high sensitivity, with a limit of detection of 0.104μM and a fast response to Co2+ (<4 min). The detection mechanism was confirmed by FT-IR, HRMS and DFT calculations Co2+ can restrict the free rotation of the C=N group and the pyrazine ring of PEPA, resulting in the enhancement of fluorescence. In addition, the recognition process of Co2+ can be realized with the naked eye (i.e., a color change from colorless to blue fluorescence). The successful detection of Co2+ in test strips and environmental water samples provides strong support for its application potential. Interestingly, the recovery rate of Co2+ detected by PEPA can reach 93% after being recovered four times. Importantly, PEPA was suitable for the fluorescence imaging of exogenous Co2+ in HeLa cells.
Related Products of 22047-25-2, 2-Acetylpyrazine has been identified as one of the volatile flavor constituents in popcorn, wheat and rye bread crust.
2-Acetylpyrazine, also known as 1-pyrazinylethanone or fema 3126, belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R’, where R = aryl group and R’=alkyl group. 2-Acetylpyrazine exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, 2-acetylpyrazine is primarily located in the cytoplasm. 2-Acetylpyrazine has a bitter, bread crust, and chip taste.
2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines.
2-Acetylpyrazine is a nitrogen containing compound that has been used in biological studies. 2-Acetylpyrazine has been shown to have inhibitory properties against the growth of prostate cancer cells and other cell lines. It also inhibits the production of fatty acids and epidermal growth factor, which are important for cellular proliferation. The inhibition is due to the photochemical properties of 2-acetylpyrazine, which cause the formation of reactive species that react with biological molecules. The reactive species may be generated by either a reaction mechanism or a reaction pathway that involve coordination geometry. 2-acetylpyrazine has also been used as a fluorescence probe for fatty acid detection in lipid bilayers and liposomes., 22047-25-2.