The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Zwitterion structure and acylative ring-opening reactions of 2-aminothiazoline-4-carboxylic acid》. Authors are Gawron, Oscar; Fernando, Joseph; Keil, John; Weismann, T. J..The article about the compound:2-Amino-4,5-dihydrothiazole-4-carboxylic acidcas:2150-55-2,SMILESS:O=C(C1N=C(N)SC1)O).Related Products of 2150-55-2. Through the article, more information about this compound (cas:2150-55-2) is conveyed.
pKA values (pK1 2.03, pK2 8.48), variation of optical rotation with pH and other phys. properties indicate that 2-aminothiazoline-4-carboxylic acid is a zwitterion in solution and in the solid state anti that pK2 can be ascribed to ionization from the ring nitrogen. Acylation of 2-aminothiazoline-4-carboxylic acid in aqueous medium is accompanied by ring opening. With Ac2O N’, S-diacetyl-N-carbamoylcysteine is obtained and with BzCl S-benzoyl-N-carbamylcysteine and 2-imino-3-benzoylthiazolidine-4-carboxylic acid are obtained. Structures of the acylated products were proven by chem. methods and by interpretation of nuclear magnetic resonance data
After consulting a lot of data, we found that this compound(2150-55-2)Related Products of 2150-55-2 can be used in many types of reactions. And in most cases, this compound has more advantages.