The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid(SMILESS: O=C(C1N=C(N)SC1)O,cas:2150-55-2) is researched.Quality Control of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid. The article 《Continuous L-cysteine production using immobilized cell reactors and product extractors》 in relation to this compound, is published in Process Biochemistry (Oxford). Let’s take a look at the latest research on this compound (cas:2150-55-2).
Methods to improve the stability of L-cysteine-producing enzymes from Pseudomonas sp. M-38, both as whole cells and as immobilized cells, were investigated for the production of L-cysteine from DL-2-amino-Δ2-thiazoline-4-carboxylic acid (DL-ATC). Among the 3 L-cysteine-producing enzymes, only L-ATC hydrolase was unstable. However, the stability of L-ATC hydrolase was significantly enhanced by the addition of 20% sorbitol. In continuous L-cysteine production, >60% of the initial activity of L-ATC hydrolase remained after 1000 h at 37° with 40% sorbitol and at 30° with 20% sorbitol. A system involving a cascade of processes using 2 packed-bed reactors with immobilized cells and 2 L-cysteine extractors with the ion-exchange resin Dowex 50W was developed to reduce product inhibition and unreacted substrate. The overall productivity of the system was 43% higher than for 2 reactors without an ion-exchange extractor.
Compounds in my other articles are similar to this one(2-Amino-4,5-dihydrothiazole-4-carboxylic acid)COA of Formula: C4H6N2O2S, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.