Bruni, Fabrizio; Selleri, Silvia; Costanzo, Annarella; Guerrini, Gabriella; Ciciani, Giovanna; Costagli, Camilla; Sacco, Cristiana; Donato, Rosa published an article about the compound: 3-(Pyridin-4-yl)-1H-pyrazol-5-amine( cas:91912-53-7,SMILESS:NC1=CC(C2=CC=NC=C2)=NN1 ).Formula: C8H8N4. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:91912-53-7) through the article.
A series of pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6-ones, I (R1 = H, Me, Ph, 2-furyl, etc., R2 = cyano, CO2Et, H, Ph, NO2, Cl, R3, R4 = H, Me), was prepared by a simple synthetic procedure based on the reaction of hydroxylamine or methoxyamine with 2,3-substituted Et 7-dimethylaminovinyl pyrazolo[1,5-a]pyrimidin-6-carboxylates II. The antimicrobial activity of the obtained compounds was evaluated on a series of standard strains of Gram pos., Gram neg. bacteria and fungi. None of the tested compounds showed significant activity.
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