The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Formation of 2-iminothiazolidine-4-carboxylic acid in the cyanobromination of lanthionine》. Authors are van Rensburg, N. J. J..The article about the compound:2-Amino-4,5-dihydrothiazole-4-carboxylic acidcas:2150-55-2,SMILESS:O=C(C1N=C(N)SC1)O).Related Products of 2150-55-2. Through the article, more information about this compound (cas:2150-55-2) is conveyed.
A 5 ml. solution of lanthionine in 0.1N HCl was added to 5 ml. 5% aqueous NaCN and the mixture treated with 1 ml. NCBr solution (prepared by adding 5% aqueous NaCN to a saturated solution of Br till the solution was just colorless). After 3 consecutive boilings for 30 secs. and cooling for 3 min., the thiol content estimation was interfered with by incomplete removal of NCBr. The reaction mixture was, therefore, boiled for 10 min., but the quantity of thiol formed was not consistent and reproducibility of the results was very poor. Paper chromatography of the products in sec-BuOH-HCOOH-H2O (75:15:10) system showed the presence of 2-iminothiazolidine-4-carboxylic acid (I). In these experiments, HCl was converted to HCN, which was expelled on boiling and probably the high pH led to the formation of the acid.
In some applications, this compound(2150-55-2)Related Products of 2150-55-2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.