The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Determination of 2-iminothiazolidine-4-carboxylic acid》. Authors are Bradham, L. S.; Catsimpoolas, Nicholas; Wood, John L..The article about the compound:2-Amino-4,5-dihydrothiazole-4-carboxylic acidcas:2150-55-2,SMILESS:O=C(C1N=C(N)SC1)O).Quality Control of 2-Amino-4,5-dihydrothiazole-4-carboxylic acid. Through the article, more information about this compound (cas:2150-55-2) is conveyed.
Procedures are described for determination of 2-iminothiazolidine-4-carboxylic acid, using diazotized sulfanilic acid or the mercury-diphenylthiocarbazone reaction. The compound should first be separated from interfering substances such as are found in urine. Paper electrophoresis, ion displacement, or chromatography suffice for this purpose.
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