New learning discoveries about 591-54-8

From this literature《Spectrum of antiviral activity of 4-aminopyrimidine N-oxides against a broad panel of tick-borne encephalitis virus strains》,we know some information about this compound(591-54-8)COA of Formula: C4H5N3, but this is not all information, there are many literatures related to this compound(591-54-8).

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Spectrum of antiviral activity of 4-aminopyrimidine N-oxides against a broad panel of tick-borne encephalitis virus strains, published in 2020-02-29, which mentions a compound: 591-54-8, Name is 4-Aminopyrimidine, Molecular C4H5N3, COA of Formula: C4H5N3.

Tick-borne encephalitis is an important human arbovirus neuroinfection spread across the Northern Eurasia. Inhibitors of tick-borne encephalitis virus (TBEV) strain Absettarov, presumably targeting E protein n-octyl-β-D-glucoside (β-OG) pocket, were reported earlier. In this work, these inhibitors were tested in vitro against seven strains representing three main TBEV subtypes. The most potent compound, 2-[(2-methyl-1-oxido-5,6,7,8-tetrahydroquinazolin-4-yl)amino]-phenol, showed EC50 values lower than 22 μM against all the tested strains. Nevertheless, EC50 values for virus samples of certain strains demonstrated a substantial variation, which appeared to be consistent with the presence of E protein not only in infectious virions, but also in non-infectious and immature virus particles, protein aggregates, and membrane complexes.

From this literature《Spectrum of antiviral activity of 4-aminopyrimidine N-oxides against a broad panel of tick-borne encephalitis virus strains》,we know some information about this compound(591-54-8)COA of Formula: C4H5N3, but this is not all information, there are many literatures related to this compound(591-54-8).

Reference:
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem