So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Osano, Mana; Jhaveri, Dishit P.; Wipf, Peter researched the compound: Ethyl oxazole-5-carboxylate( cas:118994-89-1 ).Category: pyrazines.They published the article 《Formation of 6-Azaindoles by Intramolecular Diels-Alder Reaction of Oxazoles and Total Synthesis of Marinoquinoline A》 about this compound( cas:118994-89-1 ) in Organic Letters. Keywords: marinoquinoline total synthesis. We’ll tell you more about this compound (cas:118994-89-1).
A new variant of the intramol. Diels-Alder oxazole (IMDAO) cycloaddition that provides direct access to 6-azaindoles was developed. The IMDAO reaction was applied in a total synthesis of the aminophenylpyrrole-derived alkaloid marinoquinoline A, also featuring the use of a Curtius reaction for preparation of a 5-aminooxazole, a propargylic C,H-bond insertion, an in situ alkyne-allene isomerization, and a ruthenium-catalyzed cycloisomerization for benzene ring annulation to the 6-azaindole.
There is still a lot of research devoted to this compound(SMILES：O=C(C1=CN=CO1)OCC)Category: pyrazines, and with the development of science, more effects of this compound(118994-89-1) can be discovered.