Reference of 109-08-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 109-08-0, name is 2-Methylpyrazine belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
Reaction of AgNO3 (33.8 mg, 0.2 mmol), methylpyrazine (mpyz)(19 mg, 0.2 mmol) and isophthalic acid (H2ipa) (33.3 mg, 0.2 mmol) took place in methanol-DMF (DMF = N,N-dimethylformamide) solvents (6 ml, v/v = 1:1) under ultrasonic treatment (160 W, 40 KHz,30 min) at 50 ¡ãC. Addition of ammonia (25percent, 0.5 mL) was found to be an efficient way to eliminate the white precipitate. The resultant solution was allowed slowly and quietly to evaporate at room temperature. The pale pink and prismatic crystals of compound 1 are obtained after several days in the darkness. The crystals were isolated by filtration and washed by deionized water and enthanol and dried in the air. Yield: ca. 80percent based on Ag. Elemental analysis: Anal. Calc. for Ag2C13H10N2O4: C, 32.94; H,2.13; N, 5.91. Found: C, 32.04; H, 2.24; N 6.09percent. Selected IR peaks(cm1): 3355 (s), 3068 (m), 2370 (w), 1606 (s), 1556 (s), 1477(m), 1429 (s), 1379 (s), 1263 (w), 1157 (w), 1062 (m), 1027 (m),943 (w), 906 (w), 821(w), 723 (s), 711 (s), 655 (m), 507 (w), 445(w), 406 (m).
The synthetic route of 2-Methylpyrazine has been constantly updated, and we look forward to future research findings.
Reference:
Article; Wang, Dan-Feng; Wang, Zhan-Hui; Zhang, Ting; Dai, Si-Min; Huang, Rong-Bin; Zheng, Lan-Sun; Inorganica Chimica Acta; vol. 415; (2014); p. 61 – 68;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem