So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Bhattacharya, Rahul; Singh, Poonam; Palit, Meehir; Waghmare, Chandrakant; Singh, Anil Kumar; Gopalan, Natarajan; Kumar, Deo researched the compound: 2-Amino-4,5-dihydrothiazole-4-carboxylic acid( cas:2150-55-2 ).COA of Formula: C4H6N2O2S.They published the article 《Time-dependent comparative evaluation of some important biomarkers of acute cyanide poisoning in rats: an aid in diagnosis》 about this compound( cas:2150-55-2 ) in Biomarkers. Keywords: forensic cyanide acute poisoning biomarker diagnosis. We’ll tell you more about this compound (cas:2150-55-2).
Objective: The study focuses on time-dependent comparative evaluation of various biomarkers of acute cyanide poisoning in rats. Methods: Blood gas (analyzer), lactate, pyruvate, cyanide, thiocyanate (spectrophotometer) and 2-amino-2-thiazoline-4-carboxylic acid (ATCA; gas chromatog.-mass spectrometry) in plasma or urine, and various physiol. parameters (polygraph) were measured. Results: Cyanide poisoning was characterized by elevated lactate, cyanide, thiocyanate and ATCA concentrations in plasma up to 15 min, 4, 16 and 24 h, resp., while high urinary thiocyanate and ATCA levels were measured between 4 and 24 h. Conclusion: ATCA concentration in plasma and urine was found to be more reliable indicator of cyanide poisoning.
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