I found the field of Chemistry very interesting. Saw the article Characteristic Profiles of Biologically Active Substances of Blood Plasma Samples from Patients with Tuberculosis Obtained by HPLC published in 2019. Formula: C5H4N2O2, Reprint Addresses Kartsova, LA (corresponding author), St Petersburg State Univ, Inst Chem, St Petersburg 198504, Russia.. The CAS is 98-97-5. Through research, I have a further understanding and discovery of Pyrazine-2-carboxylic acid
Toxic metabolites (N-acetylisoniazid, pyrazinoic acid, and desacetylrifampicin) of first-line anti-tuberculosis drugs (ethambutol, pyrazinamide, rifampicin, and isoniazid) are identified by liquid chromatography-mass spectrometry, which is important in selecting the required dosages of these drugs for the maximum therapeutic effects and the reduction of side effects. Characteristic chromatographic profiles of blood plasma samples from donors with pulmonary tuberculosis (pathology) and a clinically healthy group (norm) are obtained and processed by principal component analysis and the k-nearest neighbor method. A perspective of this approach for obtaining of additional diagnostic criteria for pulmonary tuberculosis is shown.
Formula: C5H4N2O2. Welcome to talk about 98-97-5, If you have any questions, you can contact Solov’eva, SA; Bessonova, EA; Kartsova, LA or send Email.
Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem