COA of Formula: C5H4N2O2. Recently I am researching about CARBOXYLIC-ACIDS; HYDROAMINATION; ISOTHIOCYANATES; CHEMISTRY; FACILE; AMINO, Saw an article supported by the University of Ottawa; NSERCNatural Sciences and Engineering Research Council of Canada (NSERC). Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Derasp, JS; Barbera, EA; Seguin, NR; Brzezinski, DD; Beauchemin, AM. The CAS is 98-97-5. Through research, I have a further understanding and discovery of Pyrazine-2-carboxylic acid
Hydroxamic acids are present in a several pharmaceuticals and agrochemicals. Synthetic strategies providing access to hydroxamic acid derivatives remain limited, typically requiring the use of nucleophilic hydroxylamine reagents. Herein, a synthesis of hydroxamates from unactivated carboxylic acids is reported making use of rare blocked (masked) O-substituted isocyanates. The applicability of this transformation was highlighted by targeting the synthesis of vorinostat and belinostat derivatives.
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Reference:
Patent; Chevron Research Company; US4732894; (1988); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem