Adding a certain compound to certain chemical reactions, such as: 144692-85-3, name is 2,3-Dichlorofuro[3,4-b]pyrazine-5,7-dione, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 144692-85-3, COA of Formula: C6Cl2N2O3
Under nitrogen, 25ml single neck flask was added 2,3-dichloro-o-pyrazine dicarboxylic anhydride 145 (2.8mmol), cyclohexylamine hydrochloride (4.8mmol), or n-butylamine hydrochloride (4.8mmol), and 5ml of acetic anhydride, the reaction at 120 1.5h, TLC showed the reaction was complete, the reaction was poured into water, solid precipitated, suction filtration, the solid was separated by column chromatography to give a white product.2,3-dichloro-6-cyclohexyl–5H- pyrrolo [3,4-b] pyrazine -5,7 (6H) – dione 146a, yield 67%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,3-Dichlorofuro[3,4-b]pyrazine-5,7-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Capital Normal University; Liao, Yi; Zhu, Rui; Tong, Linlin; Guo, Zhangbin; (14 pag.)CN105669704; (2016); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem