In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 58138-79-7, name is 2,6-Diiodopyrazine belongs to pyrazines compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 2,6-Diiodopyrazine
1. 2-Iodo-6-dimethylaminopyrazine A solution of 2,6-diiodopyrazine (6 g, 18.1 mmol) in methanol (50 ml) and dimethylamine (40% aqueous solution, 200 ml) was heated at reflux for 1 h. The methanol was removed under vacuum, the aqueous saturated with potassium carbonate and extracted with dichloromethane (3*100 ml). The combined extracts were dried (Na2 SO4), evaporated and the residue purified by chromatography through silica-gel eluding with dichloromethane. The product (4 g) was obtained as a low melting solid, m.p. 46-48 C., m/e 249 (M+); delta (360 MHz, CDCl3) 3.10 (6H, s, 2*Me); 7.87 (1H, s, pyrazine-H); 8.01 (1H, s, pyrazine-H).
The synthetic route of 58138-79-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Merck Sharp & Dohme Limited; US5260293; (1993); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem