Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 69214-33-1, name is 8-Chloroimidazo[1,2-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 69214-33-1
A solution of 8chioroimidazo[i,2a1pyrazine (730 mg, 4.8 mrnol) and NCS (955 mg, 7,2mrnol) in MeCN/DCE (10 rnL/5 rnL ) was heated to 90 C overnight. After LCMS indicated thatstarting material disappeared, the mixture was poured into water (20 mL) and extracted with DCM (20 mL x 3). The combined organic layer was washed with water (20 rnL) and brine (20 mL), dried over anhydrous sodium sulfate, filtered and concentrated in vacuo, The residue was purified by chromatography on silica (3% FtOAc in petroleum ether) to give the title compound(700 mg) as a yellow solid. LRMS miz (M+H) 188.1, 190.1 found, 188.1, 190.1 required.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 69214-33-1.
Reference:
Patent; MERCK SHARP & DOHME CORP.; LIVERTON, Nigel; KUDUK, Scott D.; BESHORE, Doug C.; MENG, Na; LUO, Yunfu; (127 pag.)WO2016/101119; (2016); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem