Related Products of 4744-50-7,Some common heterocyclic compound, 4744-50-7, name is 2,3-Pyrazinecarboxylic anhydride, molecular formula is C6H2N2O3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of an appropriate cyclic imides 1-14 (5.0 mmol), 4-(hydrazinecarbonyl)benzenesulfonamide (15) (1.08 g, 5.0 mmol), and anhydroussodium acetate (0.69 g, 5.0 mmol) in glacial acetic acid(20 mL) was heated under reflux for 12 h. After cooling the reactionmixture, the precipitate obtained was filtered, washed with water, driedand re-crystallised from acetic acid.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2,3-Pyrazinecarboxylic anhydride, its application will become more common.
Reference:
Article; Abdel-Aziz, Alaa A.-M.; El-Azab, Adel S.; Ghiaty, Adel H.; Gratteri, Paola; Supuran, Claudiu T.; Nocentini, Alessio; Bioorganic Chemistry; vol. 83; (2019); p. 198 – 204;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem