Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 486424-37-7, name is 3-Amino-6-bromopyrazine-2-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 486424-37-7
Triethylamine (0.48 mL, 3.44 mmol) was added to a mixture of 3-amino-6-bromo-2- pyrazinecarboxylic acid (0.25 g, 1.15 mmol; described in: Ellingson, R. C.; Henry, R. L. J. Am. Chem. Soc. 1949,2798-2800), 0- (BENZOTRIAZOL-1-YL)-NNN’, N’-TETRAMETHYLURONIUM tetrafluoroborate (0.405 g, 1.26 mmol) and 1-HYDROXYBENZOTRIAZOLE (0.17 g, 1.26 mmol) in N,N-dimethylformamide/acetonitrile, (1: 1, 5ML). After stirring for 0.5 h at room temperature, 3-methoxyaniline (0.15 ML, 1. 38 mmol) was added and the resulting mixture was stirred overnight at room temperature. Water (5-10 mL) was added and the precipitate was filtered off and washed with water to give 0.25 g (68% yield) of a yellow solid: MS (ESP) m/z 323,325 (M++1).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 486424-37-7.
Reference:
Patent; ASTRAZENECA AB; WO2004/55006; (2004); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem