Research on new synthetic routes about 768-05-8

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Pyrazinoic acid hydrazide, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 768-05-8, name is Pyrazinoic acid hydrazide, belongs to pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 768-05-8, COA of Formula: C5H6N4O

To a stirred solution of hydrazide (3) (12 mmol) and KOH (10.8 mmol) in ethanol (25 mL), carbon disulde (CS2) (13.2 mmol) was slowly added. Then, the resulting mixture was stirred at room temperature for 8 h until the (4) precipitated from the solvent, collected using suction filtration and dried, and followed by recrystallization in ethanol.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Pyrazinoic acid hydrazide, and friends who are interested can also refer to it.

Reference:
Article; Zhang, Fei; Wen, Qing; Wang, She-Feng; Shahla Karim, Baloch; Yang, Yu-Shun; Liu, Jia-Jia; Zhang, Wei-Ming; Zhu, Hai-Liang; Bioorganic and Medicinal Chemistry Letters; vol. 24; 1; (2014); p. 90 – 95;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem