Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 486460-21-3, name is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C6H7F3N4
General procedure: Nucleophilic reagent (2 mmol), trimethylamine (5 mmol) and S3(2 mmol) were dissolved in N,N-dimethylformamide (2 mL) at 0 C.The reaction mixture was stirred for 2e10 h, poured into water(10 mL), and extracted by ethyl acetate (30 mL) in two times. Thecombined organic layer was washed by saturated brine andconcentrated to give the crude residue, which was purified byrecrystallization or flash chromatography.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 486460-21-3.
Reference:
Article; Xing, Jing; Zhang, Rukang; Jiang, Xiangrui; Hu, Tianwen; Wang, Xinjun; Qiao, Gang; Wang, Junjian; Yang, Fengling; Luo, Xiaomin; Chen, Kaixian; Shen, Jingshan; Luo, Cheng; Jiang, Hualiang; Zheng, Mingyue; European Journal of Medicinal Chemistry; vol. 163; (2019); p. 281 – 294;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem