Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 27398-39-6, name is 3-Chloropyrazine-2-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 27398-39-6
3-Cl-POA (1.0 g, 6.3 mmol) was dispersed in dry toluene (approx. 50 mL) with thionyl chloride (1.4 mL, 18.9 mmol, 3 equiv.) and a catalytic amount (1-2 drops) of N,N-dimethylformamide (DMF). The reaction mixture in round bottomed flask was stirred and heated in an oil bath under a condenser at 95 °C for approximately 1 h. Solvents were evaporated in vacuo and the residue was azeotroped with dry toluene (3 × 20 mL) to remove the unreacted SOCl2 to yield crude acyl chloride [43] as brown solid, which was used without further purification.
According to the analysis of related databases, 27398-39-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Semelkova, Lucia; Konecna, Klara; Paterova, Pavla; Kubicek, Vladimir; Kunes, Jiri; Novakova, Lucie; Marek, Jan; Naesens, Lieve; Pesko, Matus; Kralova, Katarina; Dolezal, Martin; Zitko, Jan; Molecules; vol. 20; 5; (2015); p. 8687 – 8711;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem