Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 889447-19-2, name is 2-Chloro-5H-pyrrolo[2,3-b]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C6H4ClN3
A mixture of 2-chloro-5i7-pyrrolo[2,3-/>]pyrazine (200.0 mg, 1.3 mmol, CAS 889447-19-2), (quinolin-5-yl)boronic acid (674.0 mg, 3.9 mmol, CAS 355386-94- 6), CU(OAC)2 (472.0 mg, 2.6 mmol) and TEA (722 pL, 5.2 mmol) in DCM (6 mL) was stirred at 40 C for 12 hours under 02 atmosphere. The reaction mixture was filtered and concentrated. The residue was purified by silica gel column (elution: petroleum ether : ethyl acetate = 100 : 0 ~ 2 : 1) to give 5-{2-chloro-57-pyrrolo[2,3-b]pyrazin-5-yl}quinoline (265.0 mg, 0.9 mmol, 73% yield) as an off-white solid. LC-MS (ESI+) m/z: 280.9 (M +H)+.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 889447-19-2.