4858-85-9, name is 2,3-Dichloropyrazine, belongs to pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of 2,3-Dichloropyrazine
Step 1: 2-chloro-3-hydrazinylpyrazi [0196] To a stirred solution of 2,3-dichloropyrazine (10.0 g, 67.6 mmol) in ethanol (95%, 120 ml) was added 85% hydrazine hydrate (25.6 mL, 338 mmol) dropwise at room temperature. The mixture was stirred for 4 hours and cooled to ice-water bath temperature. The resulting precipitate was isolated by filtration and washed with cold ethanol (95%) to give the title compound as a light yellow powder (6.5 g, 67%) which was used in the next step without further purification.
The synthetic route of 4858-85-9 has been constantly updated, and we look forward to future research findings.