Related Products of 13924-95-3, The chemical industry reduces the impact on the environment during synthesis 13924-95-3, name is Methyl 5-hydroxypyrazine-2-carboxylate, I believe this compound will play a more active role in future production and life.
2-hydroxy-5-carbomethoxy-pyrazine (15.4 g) was dissolved in phosphorus oxychloride (100 ml) and several drops of dimethylformamide were added, followed by stirring with heating at 140C for 3 hours. After the reaction solution was poured into ice water and extracted with chloroform, the organic layer was washed with an aqueous saturated sodium hydrogen carbonate solution and saturated brine, dried and then concentrated. The resulting crystal was collected by filtration and washed with ether to obtain 2-chloro-5-carbomethoxy-pyrazine (14.0 g).
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