486460-21-3, name is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine, belongs to pyrazines compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 486460-21-3
Example 19E (66 mg, 0.18 mmol), 3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine (prepared as described in D. Kim et al, J. Med. Chem. 2005, 48, 141-151). 41.6 mg, 0.216 mmol), and triethyl amine (62.6 mL, 0.45 mumol) were mixed in 1 mL of methylene chloride and stirred for two days. The mixture was then purified by flash chromatography (eluting with 60-70% ethyl acetate/hexane) to give the desired nitro amine.
The synthetic route of 486460-21-3 has been constantly updated, and we look forward to future research findings.