6705-33-5, The chemical industry reduces the impact on the environment during synthesis 6705-33-5, name is Pyrazin-2-ylmethanol, I believe this compound will play a more active role in future production and life.
To a solution of pyrazin-2-ylmethanol (550 mg, 5 mmol, 1 equiv) and triethylamine (1.52 mL, 11 mmol, 2.2 equiv) in DCM (15 mL) was added MsCl (1.26 g, 11 mmol, 2.2 equiv) dropwise. The resulting mixture was stirred at room temperature for 2 hours. The reaction mixture was diluted with water and extracted with DCM (3*50 mL). The combined organic phase were dried over MgSCL and concentrated in vacuo to afford the title compound pyrazin-2-ylmethyl methanesulfonate as a yellow solid which was used for the next step without any further purification (940 mg crude). LC-MS: m/z 189.0 (M+H)+
The chemical industry reduces the impact on the environment during synthesis Pyrazin-2-ylmethanol. I believe this compound will play a more active role in future production and life.
Reference:
Patent; ANNAPURNA BIO INC.; TANG, Haifeng; BOYCE, Sarah; HANSON, Michael; NIE, Zhe; (213 pag.)WO2019/169193; (2019); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem