In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 33332-28-4 as follows. category: Pyrazines
p. N-(6-Chloro-2-pyrazinyl)-4-hydroxy-2-methyl-2H-naphtho[2, 1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide, m.p. 209¡ã-210¡ã C (from ethanol), from 2-methyl-4-(1-pyrrolidyl)-2H-naphtho[2,1 -e]-1,2-thiazine-3-carboxylic acid chloride-1,1-dioxide and 2-amino-6-chloro-pyrazine.
According to the analysis of related databases, 33332-28-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Boehringer Ingelheim GmbH; US3992535; (1976); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem