Electric Literature of 22047-25-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 22047-25-2, name is Acetylpyrazine belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
To a stirred solution of acetylpyrazine (0.041 g, 0.30 mmol) and ground 3 A dried molecular sieves in methanol was added dropwise 4,4’methyledianiline (0.029 g, 0.15 mmol) in methanol and a few drops of glacial acetic acid. The mixture was heated under reflux for 24 h. The molecular sieves were removed by filtration and the filtrate treated with FeCl2 4H2O (0.019 g, 0.10 mmol) and refluxed for 2 hours. The purple solution was treated with methanolic ammoniumhexafluorophosphate solution, the resulting precipitate were filtered off and dried over P4O10. recrystalization from CH3CN/diisopropylether afforded 0.052g, yield 58% of purple crystals of [Fe2L3](PF6) 1HNMR (300MHz, CD3CN, 298K) d = 9.68 (1H, br, H6/5) 8.82 (1H, br, H3), 7.37 (2H, br, H6/5, HPh), 6.77 (1H, d, J = 7.0 Hz, HPh), 6.77 (1H, d, J = 7.0 Hz, HPh), 4.65 (1H, d, J = 6.4 Hz, HPh), 4.04 (1H, s, CH2), 2.47 (3H, s, CH3).
The synthetic route of Acetylpyrazine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; UNIVERSITY OF WARWICK; WO2005/33119; (2005); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem