Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 123-32-0, Name is 2,5-Dimethylpyrazine, molecular formula is , belongs to Pyrazines compound. In a document, author is Chen, Jin-Ming, Quality Control of 2,5-Dimethylpyrazine.
A Domino Fusion of an Organic Ligand Depended on Metal-Induced and Oxygen Insertion, Unraveled by Crystallography, Mass Spectrometry, and DFT Calculations
Herein, the reaction of (1-methyl-1 H-benzo[d]imidazol-2-yl)methanamine (L1) with Co(H2O)(6)Cl-2, in CH3CN at 120 degrees C, leading to the 2,3,5,6-tetrakis(1-methyl-1 H-benzo[d]imidazol-2-yl)pyrazine (3), isolated as a dimeric cluster {[Co-2(II)(3)Cl-4].2 CH3CN} (2), is reported. When O-2 and H2O are present, (1-methyl-1 H-benzo[d]imidazole-2-carbonyl)amide (HL1 ‘) is first formed and crystallized as [Co-III(L1)(2)(L1 ‘)]Cl-2.2 H2O (4) before fusion of HL1 ‘ with L1, giving 1-methyl-N-(1-methyl-1 H-benzo[d]imidazol-2-carbonyl)-1 H-benzo[d]imidazol-2-carboxamide (HL2 ”) forming a one-dimensional (1D) chain of [Co-3(II)(L2 ”)(2)Cl-4](n) (5). The combination of crystallography and mass spectrometry (ESI-MS) of isolated crystals and the solutions taken from the reaction as a function time reveal seven intermediate steps leading to 2, but six steps for 5, for which a different sequence takes place. Control and isotope labeling experiments confirm the two carbonyl oxygen atoms in 5 originate from both air and water. The dependence on the metals, compared with FeCl3.6 H2O leading to a stable triheteroarylmethyl radical, is quite astounding, which could be attributed to the different oxidation states of the metals and coordination modes confirmed by DFT calculations. This metal and valence dependent process is a very useful way for selectively obtaining these large molecules, which are unachievable by common organic synthesis.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 123-32-0, in my other articles. Quality Control of 2,5-Dimethylpyrazine.