Electric Literature of 22047-25-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 22047-25-2, name is Acetylpyrazine belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
To a solution of 5-methyl-2-furaldehyde (24.59 mmol) and 2-acetylpyrazine (24.59 mmol)was added 20 mL of ethanol. The mixture was dissolved first before addition of 2% ethanolicKOH (9.63 mL) at 0C and stirred for 24 hr at 25C. After the completion of reaction wasmonitored by TLC, crushed ice was added to the reaction mixture. The precipitate formedwas filtered, washed with cold water, dried, and recrystallized by absolute ethanol. of 3-(5-methylfuran-2-yl)-1-(pyrazin-2-yl)prop-2-en-1-one (5) Yellow crystal (77.4% yield) m.p. 113.4-115.7C, IR (cm-1): 3104 (C-H aromatic), 2923 (CHaliphatic), 1662 (C=O), 1598 (C=C olefinic), 1558 and 1518 (C=C aromatic). 1H NMR(400 MHz, CDCl3): Table 1); 13C NMR (100 MHz, CDCl3): Table 1; Found (ESI): 215.0815[M+ H+], (C12H11N2O2 requires 215.0821).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Acetylpyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Mokhtar, Zakiah; Jamalis, Joazaizulfazli; Bohari, Siti Pauliena Mohd; Rosli, Mohd Mustaqim; Fun, Hoong-Kun; Molecular Crystals and Liquid Crystals; vol. 631; 1; (2016); p. 119 – 131;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem