Reference of 123-32-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 123-32-0, name is 2,5-Dimethylpyrazine, This compound has unique chemical properties. The synthetic route is as follows.
Example 7 BSc4354: 2,5-Bis(4-methoxystyryl)pyrazine Synthesis: 2,5-Dimethylpyrazine (0.125 g, 1.16 mmol) is dissolved in 10 ml dimethylformamide, followed by addition of 4-methoxybenzaldehyde (0.315 g, 2.32 mmol) and potassium-t-butoxide (0.26 g, 2.32 mmol) The solution is heated for 4 h to 80 C. and allowed to cool to room temperature. In this process, a solid crystallizes out. The solution containing the crystallized solid is filtered and washed with ethyl acetate. After drying under high-vacuum, 0.370 g (yield: 93%) of the product BSc4354 is obtained as yellow solid.1H-NMR (CDCl3, 500 MHz): delta=8.54 (s, 2H), 7.67 (d, J=16 Hz, 2H), 7.55 (d, J=9 Hz, 4H), 7.04 (d, J=16 Hz, 2H), 6.93 (d, J=9 Hz, 4H, 3.85 (s, 6H) ppm13C-NMR (CDCl3, 125 MHz): delta=158.3, 146.9, 141.0, 131.7, 126.7, 120.0, 112.3, 53.4 ppm.
The chemical industry reduces the impact on the environment during synthesis 2,5-Dimethylpyrazine. I believe this compound will play a more active role in future production and life.
Reference:
Patent; KLINIKUM DARMSTADT GMBH; TECHNISCHE UNIVERSITAT DARMSTADT; LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN; Schmidt, Boris; Kieser, Daniel; Bolaender, Alexander; Herms, Jochen; Haussen, Roland Heyny-Von; Gu, Jiamin; US2013/287700; (2013); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem