Related Products of 123-32-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 123-32-0, name is 2,5-Dimethylpyrazine belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
A solution of m-CPBA (70% purity, 100.0 g, 405.63 mmol) in ethyl acetate (150 mL) was washed with brine (150 mL). The organic layer was separated, dried over MgSO4 and filtered. The filtrate was added to a solution of 2,5-dimethylpyrazine 2 (20.20 mL, 184.94 mmol) in ethyl acetate (50 mL) and the resulting solution was stirred for 24 h at rt. The white solid precipitated was filtered, washed by ethyl acetate (3×100 mL) and dried to give the title compound 6 (23.5 g, 90%) as a white crystalline solid. M.p.: 286 C (dec.).1 1H MNR (200 MHz, D2O): d 8.48 (s, 2H), 2.42 (s, 6H). 13C MNR (50 MHz, D2O): d 145.8, 136.0, 13.7. HRMS (DCI+CH4) Calcd. for C6H9N2O2 [M+H]+: 141.0664. Found: 141.0674.
The synthetic route of 2,5-Dimethylpyrazine has been constantly updated, and we look forward to future research findings.
Reference:
Article; Das, Sajal Kumar; Frey, Joseph; Tetrahedron Letters; vol. 53; 30; (2012); p. 3869 – 3872;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem